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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">periodontology</journal-id><journal-title-group><journal-title xml:lang="ru">Пародонтология</journal-title><trans-title-group xml:lang="en"><trans-title>Parodontologiya</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3759</issn><issn pub-type="epub">1726-7269</issn><publisher><publisher-name>Russian Periodontal Association (RPA)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3759-2024-998</article-id><article-id custom-type="elpub" pub-id-type="custom">periodontology-1009</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group></article-categories><title-group><article-title>Саркоидоз: проявления в полости рта (клинический случай)</article-title><trans-title-group xml:lang="en"><trans-title>Sarcoidosis: oral manifestations (case report)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9980-0969</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волков</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkov</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Волков Евгений Алексеевич, доктор медицинских наук, профессор кафедры терапевтической стоматологии и пародонтологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Evgeny A. Volkov, DMD, Professor, Department of the Restorative Dentistry and Periodontology</p><p>Moscow</p></bio><email xlink:type="simple">volkov50@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-3678-6503</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васюкова</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasyukova</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васюкова Ольга Михайловна, кандидат медицинских наук, доцент, ассистент кафедры терапевтической стоматологии и пародонтологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Olga M. Vasyukova, DMD, PhD, Docent, Assistant Professor, Department of the Restorative Dentistry and Periodontics</p><p>Moscow</p></bio><email xlink:type="simple">vasyukova7@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0206-0026</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блашкова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Blashkova</surname><given-names>Y. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Блашкова Юлия Валерьевна, аспирант кафедры терапевтической стоматологии и пародонтологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Yulia V. Blashkova, DMD, PhD student, Department of the Restorative Dentistry and Periodontology</p><p>Moscow</p></bio><email xlink:type="simple">blashkova.j@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4141-1370</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Атрушкевич</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Atrushkevich</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Атрушкевич Виктория Геннадьевна, доктор медицинских наук, профессор, заведующая кафедрой терапевтической стоматологии и пародонтологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Victoria G. Atrushkevich, DMD, PhD, DSc, Professor, Head of the Department of Restorative Dentistry and Periodontology</p><p>Moscow</p></bio><email xlink:type="simple">atrushkevichv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский университет медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian University of Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>17</day><month>10</month><year>2024</year></pub-date><volume>29</volume><issue>3</issue><fpage>341</fpage><lpage>348</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Волков Е.А., Васюкова О.М., Блашкова Ю.В., Атрушкевич В.Г., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Волков Е.А., Васюкова О.М., Блашкова Ю.В., Атрушкевич В.Г.</copyright-holder><copyright-holder xml:lang="en">Volkov E.A., Vasyukova O.M., Blashkova Y.V., Atrushkevich V.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.parodont.ru/jour/article/view/1009">https://www.parodont.ru/jour/article/view/1009</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Саркоидоз – мультисистемное гранулематозное заболевание неизвестной этиологии, которое обычно проявляется двусторонними хилярными аденопатиями, легочными инфильтратами, поражениями глаз и кожи, десны, слизистой оболочки рта. Данный клинический случай отображает проявление симптомов редкого системного заболевания в полости рта. Гипертрофия десны и мягкотканные новообразования на слизистой оболочке губ стали первыми признаками заболевания. После длительного обследования пациентка проходила лечение у стоматолога и ревматолога, что дало возможность добиться стойкой ремиссии заболевания.</p><p>Описание клинического случая. В статье представлен клинический случай проявления саркоидоза в полости рта в виде гипертрофии десны и мягкотканного образования на верхней губе. Как правило, диагноз «саркоидоз» регистрируется у пациентов до появления стоматологических симптомов. Диагностика соматического заболевания с первичной локализацией симптомов в полости рта представляет особую трудность, поскольку врачи-стоматологи не всегда знакомы с клиническими признаками общих заболеваний. При подозрении на саркоидоз необходимо исследовать слизистую оболочку полости рта, а системный саркоидоз должен быть включен в дифференциальную диагностику гранулематозных поражений полости рта.</p></sec><sec><title>Заключение</title><p>Заключение. Своевременно начатая терапия может существенно повысить качество и продолжительность жизни пациента.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Sarcoidosis is a multisystem granulomatous disease of unknown origin, commonly presenting with bilateral hilar lymphadenopathy, pulmonary infiltrates, and involvement of the eyes, skin, gums, and oral mucosa. This clinical case illustrates the oral manifestations of this rare systemic disease. Gingival hypertrophy and soft tissue lesions on the lip mucosa were the initial signs of the condition. Following an extended diagnostic process, the patient underwent treatment by both a dentist and a rheumatologist, leading to a stable remission of the disease.</p></sec><sec><title>Case description</title><p>Case description. This article presents a clinical case of sarcoidosis manifesting in the mouth as gingival hypertrophy and a soft tissue lesion on the upper lip. In most cases, a diagnosis of sarcoidosis is made before any oral symptoms appear. Diagnosing a systemic disease based on primary oral symptoms poses a unique challenge, as dental professionals may not always be familiar with the oral manifestations of systemic conditions. In cases of suspected sarcoidosis, the oral mucosa should be thoroughly examined, and systemic sarcoidosis should be considered in the differential diagnosis of granulomatous lesions in the mouth.</p></sec><sec><title>Conclusion</title><p>Conclusion. Early initiation of treatment can significantly improve the patient's quality of life and prognosis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>саркоидоз</kwd><kwd>неказеифицирующиеся гранулемы</kwd><kwd>гипертрофия десны</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Sarcoidosis</kwd><kwd>non-caseating granulomas</kwd><kwd>gingival hypertrophy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин АГ, Авдеев СН, Айсанов ЗР, Баранова ОП, Борисов СЕ, Геппе НА, и др. Саркоидоз: федеральные клинические рекомендации по диагностике и лечению. Пульмонология. 2022;32(6):806-833. doi: 10.18093/0869-0189-2022-32-6-806-833</mixed-citation><mixed-citation xml:lang="en">Chuchalin AG, Avdeev SN, Aisanov ZR, Baranova OP, Borisov SE, Geppe NA, et al. Sarcoidosis: federal clinical guidelines for diagnosis and treatment. 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