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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">periodontology</journal-id><journal-title-group><journal-title xml:lang="ru">Пародонтология</journal-title><trans-title-group xml:lang="en"><trans-title>Parodontologiya</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3759</issn><issn pub-type="epub">1726-7269</issn><publisher><publisher-name>Russian Periodontal Association (RPA)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3759-2019-24-2-121-126</article-id><article-id custom-type="elpub" pub-id-type="custom">periodontology-235</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH</subject></subj-group></article-categories><title-group><article-title>Оптимизация сроков поддерживающей пародонтальной терапии при использовании фотоактивированной дезинфекции</article-title><trans-title-group xml:lang="en"><trans-title>Optimization of the terms of supportive periodontal therapy using photoactivated disinfection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4141-1370</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Атрушкевич</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Atrushkevich</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор</p><p>Кафедра пародонтологии </p><p>Москва</p></bio><bio xml:lang="en"><p>PhD, MD, professor </p><p>Department of Periodontology </p><p>Moscow</p></bio><email xlink:type="simple">atrushkevichv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8026-0800</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орехова</surname><given-names>Л. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Orekhova</surname><given-names>L. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор</p><p>Кафедра терапевтической стоматологии и пародонтологии </p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>PhD, MD, professor, chief of the department </p><p>Department of Dentistry Restorative and Periodontology</p><p> </p></bio><email xlink:type="simple">prof_orekhova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Янушевич</surname><given-names>О. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Yanushevich</surname><given-names>O. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, член-корреспондент РАН</p><p>Кафедра пародонтологии </p><p>Москва</p></bio><bio xml:lang="en"><p>PhD, MD, professor, rector </p><p>Department of Periodontology </p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколова</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolova</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук</p><p>Кафедра пародонтологии </p><p>Москва</p></bio><bio xml:lang="en"><p>PhD </p><p>Department of Periodontology </p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобода</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Loboda</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, доцент</p><p>Кафедра терапевтической стоматологии и пародонтологии </p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>PhD, professor </p><p>Department of Dentistry Restorative and Periodontology </p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Московский государственный медико-стоматологический университет им. А.И. Евдокимова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Yevdokimov Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First Saint Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2019</year></pub-date><volume>24</volume><issue>2</issue><fpage>121</fpage><lpage>126</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Атрушкевич В.Г., Орехова Л.Ю., Янушевич О.О., Соколова Е.Ю., Лобода Е.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Атрушкевич В.Г., Орехова Л.Ю., Янушевич О.О., Соколова Е.Ю., Лобода Е.С.</copyright-holder><copyright-holder xml:lang="en">Atrushkevich V.G., Orekhova L.Y., Yanushevich O.O., Sokolova E.Y., Loboda E.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.parodont.ru/jour/article/view/235">https://www.parodont.ru/jour/article/view/235</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность: целью исследования явилось определение сроков проведения поддерживающей пародонтальной терапии при использовании фотодинамической терапии (ФДТ) и озонотерапии (ОЗТ) в дополнение к базовой терапии (БТ) заболеваний пародонта.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: нами обследованы 57 пациентов (средний возраст 49,30 ± 1,02 года) с хроническим генерализованным пародонтитом, разделенных на группы: БТ + ФДТ, БТ + ОЗТ и только БТ. Образцы содержимого пародонтальных карманов подвергали экстракции ДНК и изучали методом ПЦР с идентификацией Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi), Tannerella forsythensis (Tf), Treponema denticola (Td), Aggregatibacter actinomycetemcomitans (Aa). Количество пародонтопатогенов и клинические параметры, включая индекс гигиены, клиническую потерю прикрепления, глубину кармана, кровоточивость при зондировании, измеряли в начале исследования, через 1,5, 3 и 6 месяцев.</p></sec><sec><title>Результаты</title><p>Результаты: результатом в группах ФДТ + БТ и ОЗТ + БТ оказалось улучшение всех клинических параметров PI, BOP, PD, CAL и уменьшение количества Pg, Td и Tf по сравнению с контрольной группой в течение всего срока наблюдения.</p></sec><sec><title>Заключение</title><p>Заключение: результаты показали дополнительные преимущества ФДТ и ОЗТ в качестве дополнительного метода лечения к БТ для пациентов с хроническим генерализованным пародонтитом.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance: to indentify if periodontal treatment which is presented by photoactivated disinfection (PAD) adjunctively to scaling and root planing (SRP) yield better outcomes than ozone therapy as an adjunct to SRP in periodontitis.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: we examined 57 (mean age 49,3 ± 1,02) patients with chronic periodontitis, divided into groups, SRP + PAD, SRP + ozone therapy and SRP alone. Subgingival plaque samples were subjected to DNA extraction and real time PCR amplifcation for detection Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi), Tannerella forsythensis (Tf), Treponema denticola (Td), Aggregatibacter actinomycetemcomitans (Aa). The amount of periodontopathogens and clinical parameters including plaque index, clinical attachment loss, pocket depth, bleeding on probing were measured at baseline, after 40, 90 and 180 days.</p></sec><sec><title>Results</title><p>Results: the results in groups of PAD+SRP and ozone therapy+SRP showed an improvement in all clinical parameters PI, BOP, PD, CAL and the quantity of Pg, Td and Tf compared to the control group during an observation period.</p></sec><sec><title>Conclusion</title><p>Conclusion: the results showed additional benefts from PAD and ozone therapy as an adjunctive treatment to SRP for patients of chronic periodontitis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический пародонтит</kwd><kwd>фотодинамическая терапия</kwd><kwd>озонотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic periodontitis</kwd><kwd>photoactivated disinfection</kwd><kwd>ozone therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Боттичелли А. 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