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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">periodontology</journal-id><journal-title-group><journal-title xml:lang="ru">Пародонтология</journal-title><trans-title-group xml:lang="en"><trans-title>Parodontologiya</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3759</issn><issn pub-type="epub">1726-7269</issn><publisher><publisher-name>Russian Periodontal Association (RPA)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3759-2019-24-4-316-322</article-id><article-id custom-type="elpub" pub-id-type="custom">periodontology-267</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH</subject></subj-group></article-categories><title-group><article-title>Значение фактора времени в изменении качественного состава зубного налета</article-title><trans-title-group xml:lang="en"><trans-title>The importance of the time factor in changing the qualitative composition of plaque</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9922-137X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ипполитов</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ippolitov</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой детской стоматологии с ортодонтией</p><p>Воронеж</p></bio><bio xml:lang="en"><p>DSc, professor, head of the Department of pediatric dentistry with orthodontics </p><p>Voronezh </p></bio><email xlink:type="simple">dsvgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6969-339X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Русанова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rusanova</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры детской стоматологии с ортодонтией </p><p>Воронеж</p></bio><bio xml:lang="en"><p>PhD, Associate Professor of the Department of pediatric dentistry with orthodontics </p><p>Voronezh </p></bio><email xlink:type="simple">dsvgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1886-6588</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Золотарева</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zolotareva</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры детской стоматологии с ортодонтией </p><p>Воронеж</p></bio><bio xml:lang="en"><p>PhD, Associate Professor of the Department of pediatric dentistry with orthodontics</p><p>Voronezh </p></bio><email xlink:type="simple">dsvgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0520-2579</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алешина</surname><given-names>Е. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleshina</surname><given-names>E. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., ассистент кафедры детской стоматологии с ортодонтией </p><p>Воронеж</p></bio><bio xml:lang="en"><p>PhD, Assistant Professor of the department of pediatric dentistry with orthodontics</p><p>Voronezh </p></bio><email xlink:type="simple">dsvgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3330-6009</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беркович</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Berkovich</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры детской стоматологии с ортодонтией </p><p>Воронеж</p></bio><bio xml:lang="en"><p>post-graduate student of the Department of pediatric dentistry with orthodontics </p><p>Voronezh </p></bio><email xlink:type="simple">dsvgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4285-2466</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фоломеева</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Folomeeva</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры детской стоматологии с ортодонтией </p><p>Воронеж</p></bio><bio xml:lang="en"><p>post-graduate student of the Department of pediatric dentistry with orthodontics </p><p>Voronezh </p></bio><email xlink:type="simple">dsvgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Воронежский государственный медицинский университет имени Н.Н. Бурденко</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education «Voronezh state medical University named after N.N. Burdenko»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>22</day><month>12</month><year>2019</year></pub-date><volume>24</volume><issue>4</issue><fpage>316</fpage><lpage>322</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ипполитов Ю.А., Русанова Т.А., Золотарева Е.Ю., Алешина Е.О., Беркович М.В., Фоломеева Д.М., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Ипполитов Ю.А., Русанова Т.А., Золотарева Е.Ю., Алешина Е.О., Беркович М.В., Фоломеева Д.М.</copyright-holder><copyright-holder xml:lang="en">Ippolitov Y.A., Rusanova T.A., Zolotareva E.Y., Aleshina E.O., Berkovich M.V., Folomeeva D.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.parodont.ru/jour/article/view/267">https://www.parodont.ru/jour/article/view/267</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>фактор времени</kwd><kwd>кариесогенность зубного налета</kwd><kwd>короткоцепочные жирные кислоты</kwd><kwd>молочная кислота</kwd></kwd-group><kwd-group xml:lang="en"><kwd>time factor</kwd><kwd>chargesagainst plaque</kwd><kwd>short-chain fatty acids</kwd><kwd>lactic acid</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Александрова О. 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