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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">periodontology</journal-id><journal-title-group><journal-title xml:lang="ru">Пародонтология</journal-title><trans-title-group xml:lang="en"><trans-title>Parodontologiya</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3759</issn><issn pub-type="epub">1726-7269</issn><publisher><publisher-name>Russian Periodontal Association (RPA)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3759-2020-25-3-256-262</article-id><article-id custom-type="elpub" pub-id-type="custom">periodontology-354</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH</subject></subj-group></article-categories><title-group><article-title>Evaluation of the effect of a diode laser on the state of periodontal pathogenic microorganisms in patients with early manifestations of chronic inflammation of periodontic tissues</article-title><trans-title-group xml:lang="en"><trans-title>Evaluation of the effect of a diode laser on the state of periodontal pathogenic microorganisms in patients with early manifestations of chronic inflammation of periodontic tissues</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3065-6831</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аль Кофиш</surname><given-names>М.А.М.</given-names></name><name name-style="western" xml:lang="en"><surname>Al-Qufaish</surname><given-names>M.A.M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мохаммед Али Мохаммед Аль Кофиш - кандидат медицинских наук, врачстоматолог стоматологического факультета Университета г. Аден</p></bio><bio xml:lang="en"><p>M.A.M. AL-QUFAISH - Associate Professor, dentist Faculty of Dentistry.</p></bio><email xlink:type="simple">alqufaesh@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1781-0291</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Усманова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Usmanova</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Усманова  Ирина Николаевна - доктор медицинских наук, профессор  кафедры терапевтической стоматологии с курсом Института дополнительного профессионального образования.</p></bio><bio xml:lang="en"><p>Usmanova  Irina N. - DSc, Professor of the Department of therapeutic dentistry with the course of Institute of additional hrofessional education.</p></bio><email xlink:type="simple">irinausma@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1145-6500</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Герасимова</surname><given-names>Л. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Gerasimova</surname><given-names>L. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Герасимова Лариса  Павловна - доктор медицинских наук, профессор, заслуженный врач РБ, заведующая кафедрой терапевтической стоматологии с курсом Института дополнительного профессионального образования.</p></bio><bio xml:lang="en"><p>Gerasimova Larisa P. - DSc, Professor, Honored Doctor of the сhief of the Department therapeutic dentistry with the course of Institute of additional hrofessional education.</p></bio><email xlink:type="simple">gerasimovalarisa@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5473-2034</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Туйгунов</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tuigunov</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Туйгунов  Марсель   Маратович - доктор медицинских наук, профессор, завeдующий кафедрой микробиологии и вирусологии.</p></bio><bio xml:lang="en"><p>Tuigunov Marcel M. - DSc, Professor, head of the Department of Microbiology  and Virology.</p></bio><email xlink:type="simple">tuygunov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1001-9587</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хуснаризанова</surname><given-names>Р. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Khusnarizanova</surname><given-names>R. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хуснаризанова  Рауза  Фазыловна - кандидат медицинских наук, доцент кафедры микробиологии и вирусологии.</p></bio><bio xml:lang="en"><p>Khusnarizanova  Rausa  F. - PhD, Associate Professor of the Department of Microbiology and Virology.</p></bio><email xlink:type="simple">roza.khusna@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1123-4438</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Iakovleva</surname><given-names>А. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлева  Анастасия Владимировна - студентка 5 курса стоматологического  факультета.</p></bio><bio xml:lang="en"><p>Iakovleva Anastasia.V. - 5th year student of the faculty of dentistry.</p></bio><email xlink:type="simple">Anastasiadantist21@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>University of Aden</institution><country>Йемен</country></aff><aff xml:lang="en"><institution>University of Aden</institution><country>Yemen</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Bashkir State Medical University</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>04</day><month>09</month><year>2020</year></pub-date><volume>25</volume><issue>3</issue><fpage>256</fpage><lpage>262</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аль Кофиш М., Усманова И.Н., Герасимова Л.П., Туйгунов М.М., Хуснаризанова Р.Ф., Яковлева А.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Аль Кофиш М., Усманова И.Н., Герасимова Л.П., Туйгунов М.М., Хуснаризанова Р.Ф., Яковлева А.В.</copyright-holder><copyright-holder xml:lang="en">Al-Qufaish M., Usmanova I.N., Gerasimova L.P., Tuigunov M.M., Khusnarizanova R.F., Iakovleva А.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.parodont.ru/jour/article/view/354">https://www.parodont.ru/jour/article/view/354</self-uri><abstract><sec><title>Relevance</title><p>Relevance. Chronic inflammation of periodontal tissues in young people.</p></sec><sec><title>Purpose</title><p>Purpose. The aim of the work was to study of the effectiveness of the influence of a diode laser on the state of the microbiome of various biotopes of the oral cavity in patients with early manifestations of chronic inflammation.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 70 patients (66.7%) with chronic gingivitis and periodontitis of mild severity, aged 23–35 years, were examined. A control group was consisted of 35 patients (33.3%) with clinically intact periodontium (CIP). Researchers in this group have the goal of determining critical values (22.9%) and conducting the proposed range of treatment and preventive measures. Clinical and microbiological research methods were used to assess the effectiveness of the proposed treatment and prophylactic complex.</p></sec><sec><title>Results</title><p>Results. Our results showed high efficiency of the treatment and prophylactic complex in the treatment of early manifestations of chronic inflammation of periodontal tissues. The use of the method of simultaneous processing of the studied biotopes of the oral cavity in the complex of treatment and prophylactic measures has a positive trend. Under the influence of this effect significant elimination of periodontal pathogens of the first order and a decrease in the degree of chronic inflammation (p &lt; 0.05) from the initial data are observed in patients with early manifestations of chronic inflammation in periodontal tissues.</p></sec><sec><title>Conclusion</title><p>Conclusion. The data obtained on the basis of the study indicate that the developed treatment and oral care are an effective method for correcting the state of the microbiome of the studied biotopes.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Chronic inflammation of periodontal tissues in young people.</p></sec><sec><title>Purpose</title><p>Purpose. The aim of the work was to study of the effectiveness of the influence of a diode laser on the state of the microbiome of various biotopes of the oral cavity in patients with early manifestations of chronic inflammation.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 70 patients (66.7%) with chronic gingivitis and periodontitis of mild severity, aged 23–35 years, were examined. A control group was consisted of 35 patients (33.3%) with clinically intact periodontium (CIP). Researchers in this group have the goal of determining critical values (22.9%) and conducting the proposed range of treatment and preventive measures. Clinical and microbiological research methods were used to assess the effectiveness of the proposed treatment and prophylactic complex.</p></sec><sec><title>Results</title><p>Results. Our results showed high efficiency of the treatment and prophylactic complex in the treatment of early manifestations of chronic inflammation of periodontal tissues. The use of the method of simultaneous processing of the studied biotopes of the oral cavity in the complex of treatment and prophylactic measures has a positive trend. Under the influence of this effect significant elimination of periodontal pathogens of the first order and a decrease in the degree of chronic inflammation (p &lt; 0.05) from the initial data are observed in patients with early manifestations of chronic inflammation in periodontal tissues.</p></sec><sec><title>Conclusion</title><p>Conclusion. The data obtained on the basis of the study indicate that the developed treatment and oral care are an effective method for correcting the state of the microbiome of the studied biotopes.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>clinically intact periodontium</kwd><kwd>chronic gingivitis</kwd><kwd>periodontitis</kwd><kwd>diode laser</kwd><kwd>Periopathogenic or periodontal pathogenic microflora</kwd></kwd-group><kwd-group xml:lang="en"><kwd>clinically intact periodontium</kwd><kwd>chronic gingivitis</kwd><kwd>periodontitis</kwd><kwd>diode laser</kwd><kwd>Periopathogenic or periodontal pathogenic microflora</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Атрушкевич В. Г., Орехова Л. Ю., Янушевич О. О., Соколова Е. Ю., Лобода Е. С. 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