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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">periodontology</journal-id><journal-title-group><journal-title xml:lang="ru">Пародонтология</journal-title><trans-title-group xml:lang="en"><trans-title>Parodontologiya</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3759</issn><issn pub-type="epub">1726-7269</issn><publisher><publisher-name>Russian Periodontal Association (RPA)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3759-2021-26-4-301-307</article-id><article-id custom-type="elpub" pub-id-type="custom">periodontology-568</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH</subject></subj-group></article-categories><title-group><article-title>Индекс гигиены полости рта и некоторые показатели ротовой жидкости у пациентов с постковидным синдромом при использовании различных зубных паст</article-title><trans-title-group xml:lang="en"><trans-title>Oral hygiene and oral fluid indices in patients with post-COVID syndrome using different kinds of toothpastes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9801-503X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сатыго</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Satygo</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сатыго Елена Александровна, доктор медицинских наук, профессор, заведующая кафедрой детской стоматологии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Elena A. Satygo, DMD, PhD, DSc, Professor, Head of the Department of Pediatric Dentistry</p><p>Saint Petersburg</p></bio><email xlink:type="simple">stom9@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6151-2021</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакулин</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakulin</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бакулин Игорь Геннадьевич, доктор медицинских наук, профессор, декан лечебного факультета, заведующий кафедрой пропедевтики внутренних болезней, гастроэнтерологии и диетологии им. С.М.  Рысса</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Igor G. , DMD, PhD, DSc, Professor, Dean of the Medical School, Head of the Department of  ntroduction to Internal Diseases, Gastroenterology and Nutrition Science named after S. M. Ryss</p><p>Saint Petersburg</p></bio><email xlink:type="simple">igbakulin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8471-6193</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лимина</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Limina</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лимина Алиса Петровна, врач-стоматолог общей практики, ординатор первого года кафедры детской стоматологии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Alisa P. Limina, general dentist, first-year resident, Department of Pediatric Dentistry</p><p>Saint Petersburg</p></bio><email xlink:type="simple">szgmustomat@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет имени И.И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Mechnikov North-Western State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>20</day><month>01</month><year>2022</year></pub-date><volume>26</volume><issue>4</issue><fpage>301</fpage><lpage>307</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сатыго Е.А., Бакулин И.Г., Лимина А.П., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Сатыго Е.А., Бакулин И.Г., Лимина А.П.</copyright-holder><copyright-holder xml:lang="en">Satygo E.A., Bakulin I.G., Limina A.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.parodont.ru/jour/article/view/568">https://www.parodont.ru/jour/article/view/568</self-uri><abstract><p>Актуальность. За последние два года в научной литературе опубликовано значительное количество данных о проявлении новой коронавирусной инфекции в полости рта во время заболевания. Однако имеются лишь единичные исследования по стоматологическому статусу у пациентов с постковидным синдромом. Цель исследования – определить индекс гигиены и некоторые показатели ротовой жидкости у пациентов с постковидным синдромом при использовании различных зубных паст.Материалы и методы. Обследованы 68 пациентов в возрасте 27-40 лет, переболевших коронавирусной инфекцией не более чем за шесть месяцев до момента начала исследования. Группу контроля составили пациенты, не болевшие коронавирусной инфекцией. На первом этапе сравнивали некоторые показатели свойств и состава ротовой жидкости у пациентов, не болевших новой коронавирусной инфекцией с такими же показателями у пациентов, переболевших коронавирусной инфекцией и имеющих постковидный синдром. На втором этапе пациенты распределены по группам в зависимости от используемой зубной пасты. У всех пациентов определяли индекс гигиены полости рта и некоторые показатели ротовой жидкости.Результаты. У пациентов с постковидным синдромом снижена скорость саливации, увеличена вязкость слюны, снижен минерализующий потенциал слюны, снижена активность лизоцима и уменьшена концентрация кателицидина LL-37 в ротовой жидкости. Установлено, что пациенты, использующие для ухода за полостью рта увлажняющую зубную пасту (R.O.C.S. Moisturizing), имели более высокие показатели скорости саливации, активности лизоцима, кателицидина LL-37, чем пациенты, использующие зубные пасты с хлоргексидином и лаурилсульфатом натрия. Также уровень гигиены полости рта у первой группы пациентов был достоверно выше.Заключение. Установлено, что у пациентов с постковидным синдромом значительно изменены некоторые показатели ротовой жидкости. Достоверно выявлено, что на показатели оказывает влияние выбор зубной пасты. Для данной группы пациентов важно использовать зубную пасту, улучшающую свойства ротовой жидкости. Использование зубной пасты R.O.C.S. Moisturizing обеспечивает улучшение свойство ротовой жидкости у пациентов с постковидным синдромом.</p></abstract><trans-abstract xml:lang="en"><p>Relevance. The scientific literature has published a considerable amount of data over the past two years on the manifestation of new COVID infection in the oral cavity during the disease. However, there are only occasional studies on the dental status of patients with the post-COVID syndrome. Purpose – to determine the oral hygiene and some oral fluid indices in patients with post-COVID syndrome using different kin ds of toothpaste.Materials and methods. The study examined 68 patients aged 27-40 years who had had a coronavirus infection not earlier than six months before the beginning of the study. The control group consisted of patients who had not been ill with COVID-19. At the first stage, we compared oral fluid characteristics and content in the patients who had not had COVID-19 with the same parameters in the patients who had had coronavirus infection and post-COVID syndrome. At the second stage, we divided the patients into groups according to the toothpaste they used. We determined the oral hygiene and oral fluid indices in all patients.Results. The patients with the post-COVID syndrome had a lower salivation rate, increased saliva viscosity, decreased saliva remineralization capacity, lower lysozyme activity and decreased cathelicidin LL-37 concentration in oral fluid. The patients, who used Moisturizing toothpaste (R.O.C.S. Moisturizing), had a higher salivation rate, lysozyme activity, cathelicidin LL-37 concentration than the patients who used toothpaste with chlorhexidine and sodium lauryl sulfate. Also, the level of oral hygiene was significantly higher in the first group.Conclusion. The study established that the oral fluid parameters significantly changed in patients with the post-COVID syndrome, and the choice of toothpaste affected those parameters. This group of patients should use toothpaste that improves the properties of the oral fluid. The use of toothpaste "R.O.C.S. Moisturizing" improved the oral fluid characteristics in patients with post-COVID syndrome.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>постковидный синдром</kwd><kwd>ротовая жидкость</kwd><kwd>зубная паста</kwd><kwd>кателицидин LL-37</kwd></kwd-group><kwd-group xml:lang="en"><kwd>post-COVID syndrome</kwd><kwd>oral fluid</kwd><kwd>toothpaste</kwd><kwd>cathelicidin LL-37</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Amorim Dos Santos J, NormandoAGC, Carvalho da Silva RL, Acevedo AC, De Luca Canto G, Sugaya N, et al. 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