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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">periodontology</journal-id><journal-title-group><journal-title xml:lang="ru">Пародонтология</journal-title><trans-title-group xml:lang="en"><trans-title>Parodontologiya</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3759</issn><issn pub-type="epub">1726-7269</issn><publisher><publisher-name>Russian Periodontal Association (RPA)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3759-2022-27-2-183-192</article-id><article-id custom-type="elpub" pub-id-type="custom">periodontology-636</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH</subject></subj-group></article-categories><title-group><article-title>Причины и клинические проявления поражений слизистой оболочки рта, возникающих на фоне COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Causes and clinical manifestations of COVID-19-related oral mucosa lesions</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5002-9352</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чудова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chudova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чудова Лариса Владимировна, кандидат медицинских наук, доцент кафедры терапевтической стоматологии</p><p>Барнаул</p></bio><bio xml:lang="en"><p>Larisa V. Chudova, MD, PhD, Associate Professor of the Department of Restorative Dentistry</p><p>Barnaul</p></bio><email xlink:type="simple">LaraCh69@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0437-0079</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Токмакова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tokmakova</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Токмакова Светлана Ивановна, доктор медицинских наук, профессор, заведующая кафедрой терапевтической стоматологии</p><p>Барнаул</p></bio><bio xml:lang="en"><p>Svetlana I. Tokmakova, MD, PhD, DSc, Professor, Head of the Department of Restorative Dentistry</p><p>Barnaul</p></bio><email xlink:type="simple">agmuterst@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2442-3361</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Луницына</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lunitsyna</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Луницына Юлия Васильевна, кандидат медицинских наук, доцент кафедры терапевтической стоматологии</p><p>Барнаул</p></bio><bio xml:lang="en"><p>Yulia V. Lunitsyna, MD, PhD, Associate Professor of the Department of Restorative Dentistry</p><p>Barnaul</p></bio><email xlink:type="simple">lunizyna.julja@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6451-9421</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зяблицкая</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zyablitskaya</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зяблицкая Ксения Викторовна, ассистент кафедры терапевтической стоматологии</p><p>Барнаул</p></bio><bio xml:lang="en"><p>Ksenia V. Zyablitskaya, MD, Assistant Professor of the Department of Restorative Dentistry</p><p>Barnaul</p></bio><email xlink:type="simple">z.kseniya87@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8387-1845</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рихтер</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Richter</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рихтер Алена Андреевна, ассистент кафедры терапевтической стоматологии</p><p>Барнаул</p></bio><bio xml:lang="en"><p>Alena A. Richter, MD, Assistant Professor of the Department of Restorative Dentistry</p><p>Barnaul</p></bio><email xlink:type="simple">shevcalen@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7198-3492</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никулина</surname><given-names>В. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikulina</surname><given-names>V. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никулина Валерия Дмитриевна, студентка института стоматологии</p><p>Барнаул</p></bio><bio xml:lang="en"><p>Valeria D. Nikulina, Undergraduate Student of the of the Institute of Dentistry</p><p>Barnaul</p></bio><email xlink:type="simple">nikylina-lera_2014@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Алтайский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Altai State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>22</day><month>05</month><year>2022</year></pub-date><volume>27</volume><issue>2</issue><fpage>183</fpage><lpage>192</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чудова Л.В., Токмакова С.И., Луницына Ю.В., Зяблицкая К.В., Рихтер А.А., Никулина В.Д., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Чудова Л.В., Токмакова С.И., Луницына Ю.В., Зяблицкая К.В., Рихтер А.А., Никулина В.Д.</copyright-holder><copyright-holder xml:lang="en">Chudova L.V., Tokmakova S.I., Lunitsyna Y.V., Zyablitskaya K.V., Richter A.A., Nikulina V.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.parodont.ru/jour/article/view/636">https://www.parodont.ru/jour/article/view/636</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. В данной обзорной статье объединены исследования российских и зарубежных ученых по основным вопросам этиологии заболеваний слизистой оболочки рта и красной каймы губ, возникающих на фоне COVID-19 и его осложнений.</p></sec><sec><title>Цель</title><p>Цель. Проанализировать причины и клиническую картину поражений слизистой оболочки рта и красной каймы губ, возникающих на фоне COVID-19 и его осложнений, а также при лечении коронавирусной инфекции.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен аналитический обзор данных литературы из библиографических источников – PubMed, Scopus, Elibrary, Googlе Scholar. В исследование включали источники литературы как на русском, так и на английском языке. Период электронного поиска составил с 01.01.2019 по 01.01.2022.</p><p>Результаты и их обсуждение. Согласно опубликованным данным литературы ранними проявлениями инфекции COVID-19 являлись потеря обоняния и вкуса. Это связывали с прямым воздействием вируса на слизистую оболочку языка и полости рта. На данный момент появилась информация о вторичных инфекциях и различного рода поражениях слизистой оболочки рта и красной каймы губ, варьирующихся от язв до разрушительных грибковых инфекций. Данные поражения могут квалифицироваться как вторичные осложнения COVID-19 или как осложнения, возникающие на фоне медикаментозной терапии.</p></sec><sec><title>Выводы</title><p>Выводы. Данное исследование поможет разработать алгоритм своевременной диагностики, маршрутизации и лечения поражений слизистой оболочки рта, связанных с SARS-CoV-2, в зависимости от причины их возникновения, для предотвращения развития более тяжелой патологии и хронизации процесса.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. The present review combines studies carried out by Russian and international scientists on the causes of oral mucosa and vermilion lesions arising in association with COVID-19, its complications and during treatment of coronaviral infection.</p></sec><sec><title>Aim</title><p>Aim. The study aimed to analyze the causes and clinical picture of oral mucosa and vermilion lesions related to COVID-19, its complications and arising during coronavirus infection treatment.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The literature data in the databases: PubMed, Scopus, eLibrary, and Google Scholar, were analytically reviewed. The study included articles in Russian and English and searched the articles published from 01.01.2019 to 01.01.2022.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. According to the literature, the loss of smell and taste are the early manifestations of COVID-19, caused by the direct virus impact on the mucous membrane of the tongue and oral cavity. The information is now available about secondary infections and various lesions of the oral muc osa and vermilion zone, ranging from ulcers to destructive fungal infections. These lesions can be classified as secondary complications of COVID-19 or as complications related to drug therapy.</p></sec><sec><title>Conclusion</title><p>Conclusion. The review will help develop an algorithm for timely diagnosis, routing and treatment of oral mucosal lesions associated with SARS-CoV-2 depending on their cause of origin to prevent the development of more severe pathology and chronification of the process.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>слизистая оболочка рта</kwd><kwd>красная кайма губ</kwd><kwd>SARS-CoV-2</kwd><kwd>коронавирусная инфекция</kwd><kwd>вторичные осложнения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>oral mucosa</kwd><kwd>vermilion</kwd><kwd>SARS-CoV-2</kwd><kwd>coronavirus infection</kwd><kwd>secondary complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бигдай ЕВ, Самойлов ВО. Обонятельная дисфункция как индикатор ранней стадии заболевания COVID-19. Интегративная физиология. 2020;1(3):187-195. Режим доступа: https://cyberleninka.ru/article/n/obonyatelnayadisfunktsiya-kak-indikator-ranney-stadii-zabolevaniyacovid-19</mixed-citation><mixed-citation xml:lang="en">Bigday EV, Samoilov VO. Olfactory dysfunction as an indicator of the early stage of COVID-19 disease. Integrative Physiology. 2020;1(3):187-195 (In Russ.). Available from: https://cyberleninka.ru/article/n/obonyatelnaya-disfunktsiya-kak-indikator-ranney-stadii-zabolevaniyacovid-19</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Brandini DA, Takamiya AS, Thakkar P, Schaller S, Rahat R, Naqvi AR. Covid-19 and oral diseases: Crosstalk, synergy or association? Reviews Medical Virologi. 2021;31(6):22-26. doi: 10.1002/rmv.2226</mixed-citation><mixed-citation xml:lang="en">Brandini DA, Takamiya AS, Thakkar P, Schaller S, Rahat R, Naqvi AR. Covid-19 and oral diseases: Crosstalk, synergy or association? Reviews Medical Virologi. 2021;31(6):22-26. doi: 10.1002/rmv.2226</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Vaira LA, Salzano G, Fois AG, Piombino P, De Riu G. Potential pathogenesis of ageusia and anosmia in COVID-19 patients. International Forum Allergy Rhinology. 2020;10(9):1103-1104. doi: 10.1002/alr.22593</mixed-citation><mixed-citation xml:lang="en">Vaira LA, Salzano G, Fois AG, Piombino P, De 5. Huang N, Pérez P, Kato T, Mikami Y, Okuda K, Gilmore RC et al. SARS-CoV-2 infection of the oral cavity and saliva. Nature Medicine. 2021;27(5):892-903. doi: 10.1038/s41591-021-01296-8</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Македонова ЮА, Поройский СВ, Гаврикова ЛМ, Афанасьева ОЮ. Проявление заболеваний слизистой полости рта у больных, перенесших COVID-19. Вестник Волгоградского государственного медицинского университета. 2021;1(77):110-115. Режим доступа: https://cyberleninka.ru/article/n/proyavleniezabolevaniy-slizistoy-polosti-rta-u-bolnyh-perenesshihcovid-19</mixed-citation><mixed-citation xml:lang="en">Martín Carreras-Presas C, Amaro Sánchez J, López-Sánchez AF, Jané-Salas E, Somacarrera Pérez ML. Oral vesiculobullous lesions associated with SARS-CoV-2 infection. Oral diseases. 2021;27(3):710-712. doi: 10.1111/odi.13382</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Huang N, Pérez P, Kato T, Mikami Y, Okuda K, Gilmore RC et al. SARS-CoV-2 infection of the oral cavity and saliva. Nature Medicine. 2021;27(5):892-903. doi: 10.1038/s41591-021-01296-8</mixed-citation><mixed-citation xml:lang="en">Kurzanov AN, Bykov IM, Ledvanov MYu. Possibilities of saliva diagnostics of COVID-19. Modern problems of science and education. 2020;6:203 (In Russ.). doi: 10.17513/spno.30404</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Martín Carreras-Presas C, Amaro Sánchez J, López-Sánchez AF, Jané-Salas E, Somacarrera Pérez ML. Oral vesiculobullous lesions associated with SARS-CoV-2 infection. Oral diseases. 2021;27(3):710-712. doi: 10.1111/odi.13382</mixed-citation><mixed-citation xml:lang="en">Gherlone EF, Polizzi E, Tetè G et al. Frequent and Persistent Salivary Gland Ectasia and Oral Disease After COVID-19. Journal of Dental Research. 2021;100(5): 464-471. doi: 10.1177/0022034521997112</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Курзанов АН, Быков ИМ, Ледванов МЮ. Возможности саливадиагностики COVID-19. Современные проблемы науки и образования. 2020;6:203-203. doi: 10.17513/spno.30404</mixed-citation><mixed-citation xml:lang="en">Khabadze ZS, Sobolev KE, Todua IM, Mordanov OS. Oral mucosal and global changes in COVID 19 (SARSCoV-2): a single center descriptive study. Endodontics Today. 2020;18(2):4-9 (In Russ.). doi: 10.36377/1683-2981-2020-18-2-4-9</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Gherlone EF, Polizzi E, Tetè G et al. Frequent and Persistent Salivary Gland Ectasia and Oral Disease After COVID-19. Journal of Dental Research. 2021;100(5):464-471. doi: 10.1177/0022034521997112</mixed-citation><mixed-citation xml:lang="en">Hüpsch-Marzec H, Dziedzic A, Skaba D, Tanasiewicz M. The spectrum of non-characteristic oral manifestations in COVID-19 – a scoping brief commentary. Medycyna Pracy. 2021;72(6):685-692. doi: 10.13075/mp.5893.01135</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Хабадзе ЗС, Соболев КЭ, Тодуа ИМ, Морданов ОС. Изменения слизистой оболочки полости рта и общих показателей при COVID 19 (SARS-CoV-2): одноцентровое описательное исследование. Эндодонтия Today. 2020;18(2):4-9. doi: 10.36377/1683-2981-2020-18-2-4-9</mixed-citation><mixed-citation xml:lang="en">Rusu LC, Ardelean LC, Tigmeanu CV, Matichescu A, Sauciur I, Bratu EA. COVID-19 and Its Repercussions on Oral Health: A Review. Medicina (Kaunas). 2021;57(11):11-89. doi: 10.3390/medicina57111189</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hüpsch-Marzec H, Dziedzic A, Skaba D, Tanasiewicz M. The spectrum of non-characteristic oral manifestations in COVID-19 – a scoping brief commentary. Medycyna Pracy. 2021;72(6):685-692. doi: 10.13075/mp.5893.01135</mixed-citation><mixed-citation xml:lang="en">Amorim Dos Santos J, Normando AGC, Carvalho da Silva RL, De Paula RM, Cembranel AC, Santos-Silva AR, Guerra ENS. Oral mucosal lesions in a COVID-19 patient: New signs or secondary manifestations? International Journal of Infectious Diseases. 2020;97:326-328. doi: 10.1016/j.ijid.2020.06.012</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rusu LC, Ardelean LC, Tigmeanu CV, Matichescu A, Sauciur I, Bratu EA. COVID-19 and Its Repercussions on Oral Health: A Review. Medicina (Kaunas). 2021;57(11):11-89. doi: 10.3390/medicina57111189</mixed-citation><mixed-citation xml:lang="en">Moser D, Biere K, Han B, Hoerl M, Schelling G, Choukér A, Woehrle T. COVID-19 Impairs Immune Response to Candida albicans. Frontiers of Immunology. 2021;12:640-644. doi: 10.3389/fimmu.2021.640644</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Amorim Dos Santos J, Normando AGC, Carvalho da Silva RL, De Paula RM, Cembranel AC, Santos-Silva AR, Guerra ENS. Oral mucosal lesions in a COVID-19 patient: New signs or secondary manifestations? International Journal of Infectious Diseases. 2020;97:326-328. doi: 10.1016/j.ijid.2020.06.012</mixed-citation><mixed-citation xml:lang="en">Salehi M, Ahmadikia K, Mahmoudi S, Kalantari S, Jamalimoghadamsiahkali S, Izadi A. et al. Oropharyngeal candidiasis in hospitalised COVID-19 patients from Iran: Species identification and antifungal susceptibility pattern. Mycoses. 2020;63(8):771-778. doi: 10.1111/myc.13137</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Moser D, Biere K, Han B, Hoerl M, Schelling G, Choukér A, Woehrle T. COVID-19 Impairs Immune Response to Candida albicans. Frontiers of Immunology. 2021;12:640-644. doi: 10.3389/fimmu.2021.640644</mixed-citation><mixed-citation xml:lang="en">Ponce JB, Tjioe KC. Overlapping findings or oral manifestations in new SARS-CoV-2 infection. Oral Diseases. 2021;27(3):781-782. doi: 10.1111/odi.13478</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Salehi M, Ahmadikia K, Mahmoudi S, Kalantari S, Jamalimoghadamsiahkali S, Izadi A. et al. Oropharyngeal candidiasis in hospitalised COVID-19 patients from Iran: Species identification and antifungal susceptibility pattern. Mycoses. 2020;63(8):771-778. doi: 10.1111/myc.13137</mixed-citation><mixed-citation xml:lang="en">Cruz Tapia RO, Peraza Labrador AJ, Guimaraes DM, Matos Valdez LH. Oral mucosal lesions in patients with SARS-CoV-2 infection. Report of four cases. Are they a true sign of COVID-19 disease? Special Care in Dentistry. 2020;40(6):555-560. doi: 10.1111/scd.12520</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Ponce JB, Tjioe KC. Overlapping findings or oral manifestations in new SARS-CoV-2 infection. Oral Diseases. 2021;27(3):781-782. doi: 10.1111/odi.13478</mixed-citation><mixed-citation xml:lang="en">Sarode GS, Sarode SC, Gadbail AR, Gondivkar S, Sharma NK, Patil S. Are oral manifestations related to SARS-CoV-2 mediated hemolysis and anemia? Medical hypotheses. 2021:146. doi: 10.1016/j.mehy.2020.110413</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Cruz Tapia RO, Peraza Labrador AJ, Guimaraes DM, Matos Valdez LH. Oral mucosal lesions in patients with SARS-CoV-2 infection. Report of four cases. Are they a true sign of COVID-19 disease? Special Care in Dentistry. 2020;40(6):555-560. doi: 10.1111/scd.12520</mixed-citation><mixed-citation xml:lang="en">Bradan Z, Gaudin A, Struillou X, Amador G, Sueidan A. Periodontal pockets: A potential reservoir for SARS-CoV-2? Medical Hypotheses. 2020;143:3. doi: 10.1016/j.mehy.2020.109907</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Sarode GS, Sarode SC, Gadbail AR, Gondivkar S, Sharma NK, Patil S. Are oral manifestations related to SARS-CoV-2 mediated hemolysis and anemia? Medical hypotheses. 2021:146. doi: 10.1016/j.mehy.2020.110413</mixed-citation><mixed-citation xml:lang="en">Bokeria LA, Sarkisyan MA, Muratov RM, Shamsiev GA. The results of detection of markers of periodontopathogenic bacteria and viruses in patients undergoing open heart surgery. Clinical physiology of blood circulation. 2010;1:156 (In Russ.). Available from: https://cfc-journal.com/catalog/detail.php?SECTION_ID=922&amp;ID=18319</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Bradan Z, Gaudin A, Struillou X, Amador G, Sueidan A. Periodontal pockets: A potential reservoir for SARS-CoV-2? Medical Hypotheses. 2020;143:3. doi: 10.1016/j.mehy.2020.109907</mixed-citation><mixed-citation xml:lang="en">Tsarev VN, Yagodina EA, Tsareva TV, Nikolaeva EN. The value of the viral-bacterial consortium in the occurrence and development of chronic periodontitis. Periodontology. 2020;25(2):84-90 (In Russ.). doi: 10.33925/1683-3759-2020-25-2-84-88</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Бокерия ЛА, Саркисян МА, Муратов РМ, Шамсиев ГА. Результаты выявления маркеров пародонтопатогенных бактерий и вирусов у пациентов, перенесших оперативное вмешательство на открытом сердце. Клиническая физиология кровообращения. 2010;1:156. Режим доступа: https://cfc-journal.com/catalog/detail.php?SECTION_ID=922&amp;ID=18319</mixed-citation><mixed-citation xml:lang="en">Nasibullina AKh, Valishin DA. Features of the microbial composition of dental plaque in patients with a confirmed diagnosis of SARS-COV-2. Problems of dentistry. 2021;17(4):56-61 (In Russ.). doi: 10.18481/2077-7566-21-17-4-56-61</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Царев ВН, Ягодина ЕА, Царева ТВ, Николаева ЕН. Значение вирусно-бактериального консорциума в возникновении и развитии хронического пародонтита. Пародонтология. 2020;25(2):84-90. doi: 10.33925/1683-3759-2020-25-2-84-88</mixed-citation><mixed-citation xml:lang="en">Belopasov VV, Zhuravleva EN, Nugmanova NP, Abdrashitova AT. Postcovid neurological syndromes. Clinical practice. 2021;12(2):69-82 (In Russ.)]. doi: 10.17816/clinpract71137</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Насибуллина АХ, Валишин ДА. Особенности микробного состава зубного налета у пациентов с подтвержденным диагнозом SARS-COV-2. Проблемы стоматологии. 2021;17(4):56-61. doi: 10.18481/2077-7566-21-17-4-56-61</mixed-citation><mixed-citation xml:lang="en">Sulaymonova GT, Shomuratova RK, Akhmedova FN. Characteristics of changes in the mucous membrane and microflora of the oral cavity during coronovirus infection. Science and education: problems and innovations. 2021:153-159 (In Russ.). Available from: https://www.elibrary.ru/item.asp?id=47246660</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Белопасов ВВ, Журавлева ЕН, Нугманова НП, Абдрашитова АТ. Постковидные неврологические синдромы. Клиническая практика. 2021;12(2):69-82. doi: 10.17816/clinpract71137</mixed-citation><mixed-citation xml:lang="en">Vagapova DM. Anosmia and ageusia during a new coronavirus infection. In the collection: hygiene, ecology and health risks in modern conditions. Materials of the XI interregional scientific and practical Internet conference of young scientists and specialists of Rospotrebnadzor with international participation. 2021;2:28-29 (In Russ.). Available from: https://elibrary.ru/item.asp?id=47374764</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Сулаймонова ГТ, Шомуратова РК, Ахмедова ФН. Характеристика изменений слизистой оболочки и микрофлоры полости рта при короновирусной инфекции. Science and education: problems and innovations. 2021:153-159. Режим доступа: https://www.elibrary.ru/item.asp?id=47246660</mixed-citation><mixed-citation xml:lang="en">Voitenkov VB, Ekusheva EV, Bedova MA. Anosmia and ageusia in patients with COVID-19 infection. Folia Otorhinolaryngologiae et Pathologiae Respiratoriae. 2020;26(3):23-28 (In Russ.). doi: 10.33848/foliorl23103825-2020-26-3-23-28</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Вагапова ДМ. Аносмия и агевзия в течении новой коронавирусной инфекции. В сборнике: гигиена, экология и риски здоровью в современных условиях. Материалы ХI межрегиональной научно-практической интернет-конференции молодых ученых и специалистов Роспотребнадзора с международным участием. 2021;2:28-29. Режим доступа: https://elibrary.ru/item.asp?id=47374764</mixed-citation><mixed-citation xml:lang="en">Glushchenko EI, Symon AM. The most likely causes of impaired smell and taste perception in COVID-19. University medicine of the Urals. 2021;7(24):16-17 (In Russ.). Available from: https://www.elibrary.ru/item.asp?id=45682996</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Войтенков ВБ, Екушева ЕВ, Бедова МА. Аносмия и агевзия у пациентов с инфекцией COVID-19. Folia Otorhinolaryngologiae et Pathologiae Respiratoriae. 2020;26(3):23-28. doi: 10.33848/foliorl23103825-2020-26-3-23-28</mixed-citation><mixed-citation xml:lang="en">Egido-Moreno S, Valls-Roca-Umbert J, Jané-Salas E, López-López J, Estrugo-Devesa A. COVID19 and oral lesions, short communication and review. Journal of Clinical and Experimental Dentistry. 2021;13(3):8. doi: 10.4317/jced.57981</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Глущенко ЕИ, Сымон АМ. Наиболее вероятные причины нарушения обоняния и восприятия вкуса при COVID-19. Университетская медицина Урала. 2021;7(24):16-17. Режим доступа: https://www.elibrary.ru/item.asp?id=45682996</mixed-citation><mixed-citation xml:lang="en">Toporkov AV, Lipnitsky AV, Polovets NV, Viktorov DV, Surkova RS. Invasive mycoses-coinfections COVID-19. Article in the open archive No. 3111961. 2021:4-6 (In Russ.). Available from: https://covid19.neicon.ru/files/4028</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Egido-Moreno S, Valls-Roca-Umbert J, Jané-Salas E, López-López J, Estrugo-Devesa A. COVID19 and oral lesions, short communication and review. Journal of Clinical and Experimental Dentistry. 2021;13(3):8. doi: 10.4317/jced.57981</mixed-citation><mixed-citation xml:lang="en">Sonia Egido Moreno, Joan Valls Roca-Umbert, Albert Estrugo Devesa. COVID-19 and oral lesions, short communication and review. Journal of Clinical and Experimental Dentistry. 2020;13(3). doi: 10.4317/jced.57981</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Топорков АВ, Липницкий АВ, Половец НВ, Викторов ДВ, Суркова РС. Инвазивные микозы-коинфекции COVID-19. Статья в открытом архиве № 3111961. 2021:4-6. Режим доступа: https://covid19.neicon.ru/files/4028</mixed-citation><mixed-citation xml:lang="en">Nejabi MB, Noor NAS, Rauﬁ N, Essar MY, Ehsan E, Shah J, Shah A, Nemat A. Tongue ulcer in a patient with COVID-19: a case presentation BMC Oral Health. 2021;21(1):273. doi: 10.1186/s12903-021-01635-8</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Sonia Egido Moreno, Joan Valls Roca-Umbert, Albert Estrugo Devesa. COVID-19 and oral lesions, short communication and review. Journal of Clinical and Experimental Dentistry. 2020;13(3). doi: 10.4317/jced.57981</mixed-citation><mixed-citation xml:lang="en">Patel J, Woolley J. Necrotizing periodontal disease: Oral manifestation of COVID-19. Oral Diseases. 2021;27(7):768-769. doi: 10.1111/odi.13462</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Nejabi MB, Noor NAS, Rauﬁ N, Essar MY, Ehsan E, Shah J, Shah A, Nemat A. Tongue ulcer in a patient with COVID-19: a case presentation BMC Oral Health. 2021;21(1):273. doi: 10.1186/s12903-021-01635-8</mixed-citation><mixed-citation xml:lang="en">Sinadinos A, Shelswell J. Oral ulceration and blistering in patients with COVID-19. Evidence Based Dentistry. 2020;21(2):49. doi: 10.1038/s41432-020-0100-z</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Patel J, Woolley J. Necrotizing periodontal disease: Oral manifestation of COVID-19. Oral Diseases. 2021;27(7):768-769. doi: 10.1111/odi.13462</mixed-citation><mixed-citation xml:lang="en">Patel J, Woolley J. Necrotizing periodontal disease: Oral manifestation of COVID-19. Oral Diseases. 2021;27(7):768-769. doi: 10.1111/odi.13462</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Sinadinos A, Shelswell J. Oral ulceration and blistering in patients with COVID-19. Evidence Based Dentistry. 2020;21(2):49. doi: 10.1038/s41432-020-0100-z</mixed-citation><mixed-citation xml:lang="en">Sinadinos A, Shelswell J. Oral ulceration and blistering in patients with COVID-19. Evidence Based Dentistry. 2020;21(2):49. doi: 10.1038/s41432-020-0100-z</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
