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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">periodontology</journal-id><journal-title-group><journal-title xml:lang="ru">Пародонтология</journal-title><trans-title-group xml:lang="en"><trans-title>Parodontologiya</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-3759</issn><issn pub-type="epub">1726-7269</issn><publisher><publisher-name>Russian Periodontal Association (RPA)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33925/1683-3759-2023-751</article-id><article-id custom-type="elpub" pub-id-type="custom">periodontology-751</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH</subject></subj-group></article-categories><title-group><article-title>Патогенетические и ассоциативные взаимосвязи параметров здоровья тканей пародонта и минеральной плотности костной ткани у женщин, проживающих в мегаполисе</article-title><trans-title-group xml:lang="en"><trans-title>Pathogenetic and associative relationships between the parameters of periodontal health and bone mineral density in women living in a megalopolis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8198-0615</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьев</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigorev</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорьев Сергей Сергеевич, доктор медицинских наук, профессор, заведующий кафедрой терапевтической стоматологии и пропедевтики стоматологических заболеваний</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Sergey S. Grigorev, DMD, PhD, DSc, Professor, Head of the Department of Operative Dentistry and Introductory Course to Dental Diseases</p><p>Ekaterinburg </p></bio><email xlink:type="simple">sergeygrig28@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1838-3535</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саблина</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sablina</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Саблина Светлана Николаевна, ассистент кафедры терапевтической стоматологии и пропедевтики стоматологических заболеваний</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Svetlana N. Sablina, DMD, Assistant Professor, Department of Operative Dentistry and Introductory Course to Dental Diseases</p><p>Ekaterinburg </p></bio><email xlink:type="simple">9122541494@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8849-8875</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Еловикова</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Elovikova</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Еловикова Татьяна Михайловна, доктор медицинских наук, профессор, профессор кафедры терапевтической стоматологии и пропедевтики стоматологических заболеваний</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Tatiana M. Elovikova, DMD, PhD, DSc, Professor, Department of Operative Dentistry and Introductory Course to Dental Diseases</p><p>Ekaterinburg </p></bio><email xlink:type="simple">ugma-elovik@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4839-4427</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Закроева</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakroeva</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Закроева Алла Геннадьевна, доктор медицинских наук, доцент, заведующая кафедрой пропедевтики внутренних болезней</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Alla G. Zakroeva, MD, PhD, DSc, Head of the Department of Introductory Course to Internal Diseases</p><p>Ekaterinburg </p></bio><email xlink:type="simple">zakroeva.alla@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1674-1957</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крохалев</surname><given-names>В. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Krokhalev</surname><given-names>V. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Крохалев Вадим Яковлевич, кандидат медицинских наук, доцент кафедры медицинской физики и цифровых технологий</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Vadim Ya. Krokhalev, MD, PhD, Associate Professor, Department of Medical Physics and Digital Technologies</p><p>Ekaterinburg </p></bio><email xlink:type="simple">vkrohalev@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7835-1084</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фоминых</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Fominykh</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мария Игоревна Фоминых, кандидат медицинских наук, доцент кафедры факультетской терапии и гериатрии</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Maria I. Fominykh, MD, PhD, Associate Professor, Department of General Internal Medicine and Geriatrics</p><p>Ekaterinburg </p></bio><email xlink:type="simple">therapy.fominykh@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5581-7136</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ургуналиев</surname><given-names>Б. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Urgunaliev</surname><given-names>B. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ургуналиев Бакыт Кубанычбекович, кандидат медицинских наук, доцент, заведующий кафедрой хирургической стоматологии и челюстно-лицевой хирургии</p><p>Бишкек</p></bio><bio xml:lang="en"><p>Bakyt K. Urgunaliev, DDS, PhD, Head of the Department of Oral and Maxillofacial Surgery</p><p>Bishkek</p></bio><email xlink:type="simple">urgunaliev@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6324-8922</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Валерия Владимировна Иванова, студентка пятого курса педиатрического факультета</p><p>Екатеринбург</p></bio><bio xml:lang="en"><p>Valeria V. Ivanova, 5th-year Student, School of Pediatrics</p><p>Ekaterinburg </p></bio><email xlink:type="simple">9126193222@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Уральский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кыргызская государственная медицинская академия имени И.К. Ахунбаева</institution><country>Кыргызстан</country></aff><aff xml:lang="en"><institution>I.K. Akhunbaev Kyrgys State Medical Academy</institution><country>Kyrgyzstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>28</day><month>11</month><year>2023</year></pub-date><volume>28</volume><issue>4</issue><fpage>369</fpage><lpage>379</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Григорьев С.С., Саблина С.Н., Еловикова Т.М., Закроева А.Г., Крохалев В.Я., Фоминых М.И., Ургуналиев Б.К., Иванова В.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Григорьев С.С., Саблина С.Н., Еловикова Т.М., Закроева А.Г., Крохалев В.Я., Фоминых М.И., Ургуналиев Б.К., Иванова В.В.</copyright-holder><copyright-holder xml:lang="en">Grigorev S.S., Sablina S.N., Elovikova T.M., Zakroeva A.G., Krokhalev V.Y., Fominykh M.I., Urgunaliev B.K., Ivanova V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.parodont.ru/jour/article/view/751">https://www.parodont.ru/jour/article/view/751</self-uri><abstract><p>Актуальность. Остеопороз и хронический пародонтит являются серьезными проблемами современности. Гипотеза об ассоциации двух указанных заболеваний до сих пор остается открытой и не позволяет поставить все точки над «и» из-за отсутствия достаточной доказательной базы.Цель исследования: выявить ассоциации между параметрами здоровья тканей пародонта и показателями, характеризующими минеральную плотность скелета у женщин постменопаузального периода.Материалы и методы. Обследованы 109 пациентов женского пола с верифицированным диагнозом «хронический генерализованный пародонтит средней степени». Участницы объединялись в две группы – основную (n = 76) и группу контроля (n = 33). Состояние МПК и системное здоровье пациентов оценивались по данным двухэнергетической рентгеновской абсорбциометрии, FRAХ® и индексу CCI. Стоматологический статус – с помощью индексов: OHI-S, CAL, PPD, PMA, ПИ, PBI. Рентгенологическая оценка устанавливалась на основании индекса Фукса для верхней и нижней челюсти, кортикального индекса MCI, выполненного по данным КЛКТ в программе Galaxis Galileos (Sirona), компьютерный томограф Orthophos SL. Статистический анализ проводился с помощью лицензионной программы Statistica 13.3. В качестве описательных статистик для переменных использовали: медиану с 25% и 75% квартилями. Условия нормальности для переменных проверяли с помощью критериев Шапиро – Уилка и χ2 (хи-квадрат). Результаты. Глубина пародонтальных карманов (PPD) в основной группе составила 4,44 (4,30 : 4,20 : 4,50). Совокупная величина потери клинического прикрепления (CAL) – 5,53 (5,50 : 5,40 : 5,80), что достоверно выше показателей в контрольной группе пациентов (р &lt; 0,001). Минеральная плотность кости позвоночника L1–L4 (Total) соответствовала остеопении (г/см2) -0,83 (-080 : -0,78 : -0,91), Т-score для позвоночника (Neck) -1,70 (-1,7 : -2,2 : -2,0). У пациентов контрольной группы признаков воспалительной деструкции по данным КЛКТ и снижения МПКТ на основании выполненной DXA не выявлялось.Заключение. Обнаружены средние, значимые (на уровне менее 0,05) корреляции между Т-score по шейке правого бедра (Neck) и параметрами, характеризующими глубину пародонтальных карманов (R = -0,39), а также между этим же параметром и потерей клинического прикрепления CAL (R = -0,37). Установлена значимая тесная отрицательная корреляция между параметром Т-score для позвоночника L1-L4 (Total) и PPD, коэффициент корреляции (R = -0,72).</p></abstract><trans-abstract xml:lang="en"><p>Relevance. Osteoporosis and chronic periodontitis are serious issues of modern life. The hypothesis that these two diseases are associated is still open-ended and doesn’t allow setting the record straight for the lack of sufficient evidence.Purpose. The study aimed to detect the relationship between periodontal health parameters and mineral bone density characteristics in postmenopausal women.Material and methods. The study examined 109 female patients with diagnosed moderate chronic generalized periodontitis (К05.31). The participants formed two groups: the main group (76 women) and the control group (33 women). Dual-energy X-ray absorptiometry, FRAХ® and CCI assessed the mineral bone density and patients’ systemic health. Dental status was evaluated using the OHI-S, CAL, PPD, PMA, PI, and PBI. X-ray assessment was based on the Fuchs index for upper and lower jaws, and the mandibular cortical index (MCI) was evaluated by CBCT scans in Galaxis Galileos software (Sirona), Orthophos SL CBCT scanner. The data were statistically analysed using licensed STATISTICA 13.3 software. In descriptive statistics for variables, the median was quartiles corresponding to the 25th percentile and the 75th percentile. The Shapiro-Wilk test and χ2 (chi-square) evaluated the normality of variables.Results. Periodontal pocket depth (PPD) was 4.44 (4.30:4.20:4.50) in the main group. The cumulative change in the clinical attachment level (CAL) was 5.53 (5.50:5.40:5.80), which was significantly higher than the control group parameters (р &lt; 0.001). Bone mineral density of L1-L4 vertebrae corresponded to osteopenia (g/cm2) -0.83 (-080: -0.78: -0.91), spine (Neck) Т-score was -1.70 (-1.7: -2.2: -2.0). In the patients of the control group, the CBCT did not show any signs of inf lammatory destruction, and the DXA test did not reveal any loss of bone mineral densit y.Conclusion. There are mean significant (less than 0.05) correlations between right femoral neck Т-scores and periodontal pocket depth parameters (R = -0.39) and between the same parameter and the clinical attachment level (CAL) (R = -0.37). A significantly high degree of negative correlation is between the spine Т-score of L1-L4 and PPD, correlation coefficient (R = -0.72).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>остеопороз</kwd><kwd>хронический генерализованный пародонтит</kwd><kwd>витамин D</kwd><kwd>постменопаузальный период</kwd><kwd>двухэнергетическая рентгеновская абсорбциометрия</kwd><kwd>инструмент FRAХ</kwd><kwd>индекс коморбидности</kwd><kwd>минеральная плотность костной ткани скелета</kwd></kwd-group><kwd-group xml:lang="en"><kwd>osteoporosis</kwd><kwd>chronic generalized periodontitis</kwd><kwd>vitamin D</kwd><kwd>postmenopause</kwd><kwd>dual-energy X-ray absorptiometry</kwd><kwd>FRAХ instrument</kwd><kwd>Charlson Comorbidity Index (CCI)</kwd><kwd>bone mineral density</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lee Y. 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