Hydrodynamic justification of the movement of microorganisms in deep regions of the periodontal
https://doi.org/10.33925/1683-3759-2020-25-1-32-36
Abstract
Relevance. The relevance of the work is determined by the fact that the efforts of doctors seeking to minimize damage that occur against the background of infectious load and deformation of periodontal tissues do not lead to a decrease in the prevalence and intensity of periodontitis. At present, it is not known how the kinetics of microorganisms increases to the semen, allowing it to overcome the pressure of the gingival fluid that is filtered through periodontal fibers.
Purpose. Since infection plays the main role in the occurrence and development of periodontitis, the aim of the work is to search for hydrodynamic mechanisms that complement the etiopathogenesis of periodontitis and explain the difficulties of its treatment.
Materials and methods. The article discusses the existence of biota in film – static and plankton – dynamic forms. As a result of a review of literature data, it is proved that the transition of biota from one form to another is determined by a wide range of factors, the most relevant of which is the quality of the environment. Staying in a biota habitat optimal for life, it transforms into a planktonic form of existence, which allows it to colonize the deeper sections of the periodontium. Colonization of surfaces is possible by diffusion, i.e. leveling the concentration of microorganisms in available volumes of biological fluids. This aspect of the etiopathogenesis of periodontal diseases is called “hydrodynamic”. Separation of the hydrodynamic aspect allows us to consider the pressure gradient in the volume of the gingival sulcus as a factor determining the direction of filtration of biological fluids.
Results. It was not possible to identify well known hydrodynamic mechanisms, that explain the possibility of microorganisms reaching the deep parts of the periodontium.
Conclusion. The article presents arguments showing that biological laws linking the quality of the environment with the dynamics of increasing population numbers do not work in the area of the periodontal sulcus, or their action is blocked by laws of a different nature. Discussing the planktonic (dynamic) form of the existence of biota, based on the laws of hydrodynamics, taking into account the type of tooth movement, it becomes possible to substantiate the hydrodynamic mechanism of reaching the deep departments of periodontal biota, to clarify preventive and therapeutic measures aimed at reducing the incidence of periodontal diseases.
About the Author
A. A. Kopytov
Belgorod National Research University
Russian Federation
Russian Federation
Kopytov Alexander Al. - DSc, candidate of sociological Sciences, Associate Professor of orthopaedicdentistry
Belgorod
References
1. L. V. Pobozhieva, I. S. Kopeckiy. The role of biofilms in the pathogenesis of inflammatory diseases of the oral cavity and methods for its elimination. Medical business. 2012;2:9-13. (In Russ.). https://cyberleninka.ru/article/n/rol-bioplenki-v-patogeneze-vospalitelnyh-zabolevaniy-polosti-rta-i-sposoby-ee-ustraneniya/viewer.
2. J. W. Costerton, G. G. Geesey K. J. Cheng. How bacteria stick. Sci. Amer. 1978;238:86-95. http://dx.doi.org/10.1038/scientificamerican0178-86.
3. A. Yu. Nikolaev, V. К. Plakunov. Is biofilm a "city of microbes" or an analogue of a multicellular organism? Microbiology. 2007;76(2):149-163. (In Russ.). https://elibrary.ru/item.asp?id=9490845.
4. A. A. Kopytov, А. М. Meirmanov, О. V. Galtsev. Bellows, calculation of the movement of the boundary of flows. Scientific reports of Belgorod State University. Series: Medicine. Pharmacy. 2011;14(105):218-222. (In Russ.). https://elibrary.ru/item.asp?id=17298115.
5. К. С Marshall. Mechanisms of bacterial adhesion at solid-water interfaces // Bacterial adhesion (mechanisms and physiological significance) / eds. D. С Savage, M. Fletcher. NY-L: Plenum Press. 1985:133-155.
6. P. E. Kolenbrander, R. N. Andersen, D. S. Blehert, R G. Egland, J. S. Fos ter, R. J. Palmer. Communication among oral bacteria. Microbiol. Mol. Biol. Rev. 2002;66(3):486-505. 10.1128 / MMBR.66.3.486-505.2002.
7. A. H. Rickard, R Gilbert, N. J. High, R E. Kolenbrander, R S. Handley. Bacterial coaggregation: an integral process in the development of multi-species biofilms. Trends Microbiol. 2003;11(2):94-100. https://elibrary.ru/item.asp?id=1455714.
8. A. A. Stafeev, G. I. Zinoviev. Biofilm at the border structural material - fixing material - tooth tissue. Institute of Dentistry. 2012;2(55):76-77. (In Russ.). https://elibrary.ru/item.asp?id=17994865.
9. A. A. Kopytov. The role of occlusal and hydrodynamic fac tors in the genesis of inflammatory processes in the teeth and methods oftheir compensation: Dis. ... Dr. honey. Sciences / Belgorod State National Research University. Belgorod. 2018:139-167. (In Russ.). https://rusneb.ru/catalog/000199_000009_008716351/.
10. R. Bos, van der Mei H.C., H. J. Busscher. Physico-chemistry of initial microbial adhesive interactions - its mechanisms and methods for study. FEMS Microbiol. Rev. 1999;23:179-230. DOI: 10.1111/j.1574-6976.1999.tb00396.x.
11. A. K. Rajvanshi. Irving Langmuir - A Pioneering Industrial. Physical Chemist. Resonance. 2008;13(7):619-626. https://doi.org/10.1007/s12045-008-0068-z.
12. А. N. Mayansky I. V. Chebotar. Strategy for controlling the bacterial biofilm process. Journal of Infectology. 2012;4(3):5-15. (In Russ.). https://elibrary.ru/item.asp?id=18765467.
13. Т. A. Rodionova, Yu. A. Nikolaev. Protective effect of reversible adhesion of the thermophilic bacterium Bacillus licheniformis 603 from n-ethyl maleimide. Microbiology. 2004; 73 (1): 133-134. (In Russ.). https://elibrary.ru/item.asp?id=17655508.
14. Yu. G. Maksimova. Heterogeneous biocatalysts based on cells of nitrile hydrolyzing bacteria and their enzymes for the transformation of nitriles and amides of carboxylic acids: dis. ... Dr. Biol, sciences. Permian. 2015:21-27. (In Russ.). https://elibrary.ru/item.asp?id=30431186.
15. H. An, R.J. Friedman. Hand book of bacterial adhesion: Principles, methods, and applications. Totowa, N.J.: Humana Press Inc. 2000:644.
16. W. С Allee. Animal aggregations, a study in general sociology. Chicago: The University of Chicago Press. 1931:456.
17. Т. A. Smirnova, L. V. Didenko, R. R. Azizbekyan, Yu. M. Romanova. Structural and functional characteristics of bacterial biofilms. Microbiology. 2010;79(4):435-446. (In Russ.). https://elibrary.ru/item.asp?id=15141820.
18. W. С Fuqua, S. С Winans, E. P. Greenberg. Quorum sensing in bacteria: the LuxR-Luxl family of cell density-responsive transcriptional regula tors. J. Bacteriol. 1994;176:269-275. DOI: 10.1128/jb.l76.2.269-275.1994.
19. T. R. De Kievit. Quorum sensing in Pseudomonas auruginosa biofilms. En viron. Microbiol. 2009;1 (2):279-288. DOI: 10.1111/j.1462-2920.2008.01792.x.
20. Yu. М. Romanova, Т. A. Smirnova, A. L. Andreev, Т. S. Ilyina, L. V. Didenko, A. L. Gunzburg. The formation of biofilms is an example of the "social be havior" of bacteria. Microbiology. 2006;75(4):481-485. (In Russ.) https://elibrary.ru/item.asp?id=17324496.
21. A. L. Bulantsev. New ideas about the ecology of bacterial populations with a communicative signal ing system. Problems of especially dangerous infections. 2006;91:11-14. (In Russ.). https://elibrary.ru/item.asp?id=9269756.
22. P. Stoodely, S. Wilson, S. Hall Stoodley, J. D. Boyle, H. M. Lappin Scott, J. W. Costerton. Growth and detachment of cell cluster from mature mixed species biofilm. Appl. Environ. Microbiol, 2001;67:5608-5613. https://doi.org/10.1128/AEM.67.12.5608-5613.2001.
23. Dynamic models in biology. Basic models of mathematical biophysics. Limited growth. Verhulst equation. (In Russ.). www.dmb.biophys.msu.ru/registry?article=32.
24. А. N. Mayansky, I. V. Chebotar. Strategy for the management of the bacterial biofilm process. Journal of Infectology. 2012;4(3):5-15. (In Russ.). https://elibrary.ru/item.asp?id=18765467.
25. A. F. Bennett, R. E. Lenski. An experimental test of evolutionary trade-offs during temperature adaptation. Proc. Natl. Acad. Sci. USA. 2007;104:8649-8654. https://doi.org/10.1073/pnas.0702117104.
26. S. V. Rusakov, М. V. Chirkov. Feedback control in a classical predator-prey system. Russian Journal of Biomechanics. 2015;19(1):65-72. (In Russ.). https://elibrary.ru/item.asp?id=23251950.
27. L. V. Polishchuk, Yu. Е. Romanovskij. The relative importance of food shortages, the press of invertebrates and vertebral predators in the dynamics of fertility and maintaining the stability of planktonic crustacean populations. Research Report No95-04-11741 (Russian Foundation for Basic Research). (In Russ.). https://www.rfbr.ru/rffi/portal/project_search/o_144249.
28. Е. I. Kiseleva. Chemosensor-guided behavioral reactions of tadpole frog tad poles RANA LESSONAE (cam.) To excreta of adult con- and heterospecific tailless amphibians of sympatric species. Sensory systems. 2009;23(2):137- 144. (In Russ.). https://elibrary.ru/item.asp?id=12136812.
29. О. A. Lukyanov, К. I. Berdyugin, A. G. Vasiliev, L A . Vasilyeva, L. E. Lukyanova, S. V. Mukhacheva, I. M. Khokhutkin, M. I. Cheprakov. Research the role of migration in the repair, regulation, and structurally-functional organization of populations (on the example of model species of small mammals) research report No97-04-48082 (Russian Foundation for Basic Research). (In Russ.). https://elibrary.ru/item.asp?id=27454958.
30. A. A. Kopytov. Dynamics of gingival fluid indices in the process of rehabilitation of patients with bridges with different inclination of supporting teeth: Author, dis. ... cand. honey. Sciences / Moscow State Medical and Dental University. Moscow. 2007:22. (In Russ.). https://elibrary.ru/item.asp?id=16161846.
31. I. A. Matveev, V. Е. Filippov, A. I. Matveev, N. G. Eremeeva. Features of the behavior of flattened mineral particles in a water stream. Non-ferrous metals. 2017;1:8-13. (In Russ.). https://elibrary.ru/item.asp?id=28806393.
32. A. A. Kopytov. The role of occlusal and hydrodynamic factors in the genesis of inflammatory processes in the teeth and methods of their compensation: Author, dis. ... Dr. med. Sciences / Belgorod State National Research University. 2018:19-21. (In Russ.). https://rusneb.ru/catalog/000199_000009_008585194/.
Review
For citations:
Kopytov AA. Hydrodynamic justification of the movement of microorganisms in deep regions of the periodontal. Parodontologiya. 2020;25(1):32-36. (In Russ.) https://doi.org/10.33925/1683-3759-2020-25-1-32-36
Views:
847
Email this article 