Topical antibiotic therapy in periodontology

Relevance. To successfully relieve the exacerbation of the inflammatory process in the periodontal tissues, it is necessary to resort to the use of systemic antibiotics to destroy the pathogenic microflora, especially in groups of patients with a burdened somatic history or with an aggressive course of periodontitis. The effectiveness of frequently used antibiotics may weaken over time and periodically conduct epidemiological studies of the sensitivity of periodontal pathogens to modern antibacterial drugs and inform specialists about the actualization of the use of these drugs in the complex treatment of periodontal diseases.

Purpose. Analysis of the actual effectiveness of the use of a modern systemic antibacterial drug based on ciprofloxacin and tinidazole to relieve exacerbation of inflammation in the complex treatment of periodontal diseases.

Materials and methods. The study involved 37 patients with signs of exacerbation of inflammation in the periodontal tissues. The range of examination included sequential determination of hygienic (OHI-s, SL) and periodontal (PMA, SBI) indices, probing of periodontal pockets and determination of loss of epithelial attachment (AED), the use of paraclinical examination methods: X-ray (CBCT) and microbiological (bacterial cultivation and subsequent determination of antibacterial sensitivity) studies, as well as Doppler ultrasound of periodontal tissues. To stop the exacerbation of the inflammatory reaction in the periodontal tissues, the patients were prescribed the drug "Cifran ST" according to the standard scheme recommended by the manufacturer under the control of a microbiological examination.

Results. Based on the data of clinical and paraclinical examination methods, there is a high antibacterial efficacy of the drug "Cifran ST" in relation to the studied periodontopathogens and relief of the exacerbation of the inflammatory reaction in the periodontal tissues 5 days after the administration of the drug.

Conclusion. The use of a broad-spectrum antibacterial drug "Cifran ST" helps to reduce inflammation during exacerbation of periodontitis.

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