Clinical and functional approaches to comprehensive treatment of periodontal diseases in children with type I diabetes
https://doi.org/10.33925/1683-3759-2021-26-1-9-19
Abstract
Relevance. The high prevalence of microvascular complications in children with type I diabetes mellitus (DM) has a serious impact on the quality of life and can result in a lower working capacity and early disability. The negative effect of the drug therapy, inability to fully comply with the acceptable age-related safety limits, specific metabolism and pharmacokinetic features in childhood – all these reveals the need to improve the patterns for comprehensive treatment of periodontal diseases in children with type I diabetes.The purpose was to explain the clinical and functional effectiveness of the combined enzyme and magnet & laser therapy in comprehensive treatment of the periodontal microcirculatory disorders in children suffering from type I diabetes.
Materials and methods. The study involved 97 children diagnosed with type I diabetes, aged 12-17 y.o., with the present disease history from 6 months to 12 years. The microcirculation was assessed by laser Doppler flowmetry. Microcirculatory disorder correction was performed by a local exposure to a running low-frequency pulsed magnetic field combined with enzyme therapy.
Results. The dynamic magnetic therapy has proven to increase the effectiveness of capillary blood flow in children with early signs of vascular congestion and hyperemia, while Phlogenzym, a polyenzyme formulation, needs to be added in cases of vascular congestion and ischemia.
Conclusion. The effectiveness of physiotherapeutic and pharmacological effect of Phlogenzym along with the dynamic magnetic therapy shows that it can be recommended as an alternative to the conventional anti-inflammatory, antiseptic and antibiotic therapy during the pre-surgical treatment and post-surgical follow-up care as well as at the maintenance phase, both in an inpatient and outpatient setting.
About the Authors
B. N. DavydovRussian Federation
Davydov, Boris N., PhD, MD, DSc, Professor, Corresponding Member of the Russian Academy of Sciences, Honored Scientist of the Russian Federation, Department of Paediatric Dentistry and Orthodontics with a course in Paediatric Dentistry, Faculty of Continuing Education
Tver
D. A. Domenyuk
Russian Federation
Domenyuk, Dmitry A., PhD, MD, DSc, Associate Professor, Department of General Dentistry and Pediatric Dentistry
Stavropol
F. V. Samedov
Russian Federation
Samedov, Fuad V., Postgraduate Student, Department of General Dentistry and Pediatric Dentistry
Stavropol
S. V. Dmitrienko
Russian Federation
Dmitrienko, Sergey V., PhD, MD, DSc, Professor, Head of the Department of Dentistry, Faculty of Postgraduate Education
Volgograd
A. V. Lepilin
Russian Federation
Lepilin, Alexander V., PhD, MD, DSc, Professor, Head of the Department of Surgical Dentistry and Oral and Maxillofacial Surgery
Saratov
References
1. Standards of Medical Care in Diabetes-2017: Summary of Revisions. Diabetes Care. 2017;40(Suppl 1):S4-S5. http://dx.doi.org/10.2337/dc17-S003.
2. Dedov, I.I., Shestakova, M.V., Vikulova, O.K. Epidemiology of diabetes mellitus in Russian Federation: clinical and statistical report according to the federal diabetes registry. Diabetes mellitus. 2017;20(1):13-41. (In Russ.). http://dx.doi.org/10.14341/DM8664.
3. Dedov, I.I., Shestakova, M.V., Mayorov, A.Y., Vikulova, O.K., Galstyan, G.R., Kuraeva, T.L., Peterkova, V.A., Smirnova, O.M., Starostina, E.G., Surkova, E.V., Sukhareva, O.Y., Tokmakova, A.Y., Shamkhalova, M.S., Jarek-Martynova, I.R., Beshlieva, D.D., Bondarenko, O.N., Volevodz, N.N., Grigoryan, O.R., Esayan, R.M., Ibragimova, L.I., Kalashnikov, V.Y., Lipatov, D.V., Shestakova, E.A. Standards of specialized diabetes care. Edited by Dedov I.I., Shestakova M.V., Mayorov A.Y. 8th edition. Diabetes mellitus. 2017;20(1S):1-121. (In Russ.). http://dx.doi.org/10.14341/DM20171S8.
4. Donnelly R., Emslie-Smith A.M., Gardner I.D., Morris A.D. ABC of arterial and venous disease: vascular complications of diabetes. BMJ. 2000;320(7241):1062-1066. http://dx.doi.org/10.1136/bmj.320.7241.1062.
5. Jarkova, I.V., Kabirova, M.F. Condition of hemodynamics of the mucous membrane of the mouth and periodontium in patients with type I diabetes mellitus. Parodontologiya. 2018;23(2):43-45. (In Russ.). http://dx.doi.org/10.25636/PMP.1.2018.2.7.
6. Basov, А.А., Ivchenko, L.G., Dmitrienko, T.D., Nuzhnaya, C.V. The role of oxidative stress in the pathogenesis of vascular complications in children with insulinable sugar diabetes. Archiv EuroMedica. 2019;9(1):136-145. http://dx.doi.org/10.35630/2199-885X/2019/9/1/136.
7. Lira-Junior R., Figueredo С. М., Bouskela Е. Severe chronic periodontitis is associated with endothelial and microvascular dysfunctions: a pilot study. J Periodontol. 2014;85(12):1648-1657. http://dx.doi.org/10.1902/jop.2014.140189.
8. Lal S., Cheng В., Kaplan S., Softness В., Greenberg Е., Goland R. S., Lalla Е., Lamster I.B. Accelerated tooth eruption in children with diabetes mellitus. Pediatrics. 2008;May;121(5):e1139-143. http://dx.doi.org/10.1542/peds.2007-1486.
9. Orekhova, L.Y., Musaeva, R.S., Loboda, E.S., Grinenko, Е.V., Gulyanov, G.Y. Assessment of peridontal vessels hemodynamics among patients with diabetes mellitus type I. Pediatric dentistry and dental profilaxis. 2020;20(1):9-14. (In Russ.). http://dx.doi.org/10.33925/1683-3031-2020-20-1-9-14.
10. Davydov, B.N., Domenyuk, D.A., Bykov, I.M., Ivchenko, L.G., Dmitrienko, S.V. Modern possibilities of clinicallaboratory and x-ray research in pre-clinical diagnostics and prediction of the risk of development of periodontal in children with sugar diabetes of the first type. Part I. Parodontologiya. 2018;24(3):4-11. (In Russ.) https://doi.org/10.25636/PMP.1.2018.3.1
Review
For citations:
Davydov BN, Domenyuk DA, Samedov FV, Dmitrienko SV, Lepilin AV. Clinical and functional approaches to comprehensive treatment of periodontal diseases in children with type I diabetes. Parodontologiya. 2021;26(1):9-19. (In Russ.) https://doi.org/10.33925/1683-3759-2021-26-1-9-19