Effectiveness of xylitol and alginate containing toothpaste in patients with chronic generalized periodontitis and type II diabetes suffering from xerostomia

Relevance. Dental disease management in type II diabetic patients suffering from xerostomia and an effective selection of oral care products moisturizing the mucus membrane have been a crucial problem for a long time. Typical for xerostomia symptoms such as dry mouth, burning tongue, pain during swallowing and eating solid food disorder interfere with choosing effective hygiene measures. The selection of a proper toothpaste that can help in effectively maintaining moisture environment in the mouth, and create comfort in the oral cavity plays a significant role.The aim of the study was to evaluate the clinical efficacy of a toothpaste containing xylitol and alginate (R.О.С.S.) in patients with generalized chronic periodontitis (GCP) and type II diabetes, suffering from xerostomia.
Materials and methods. 40 patients, (mean age 58 ± 5.1 years, min = 52.5, max = 64) with moderate GCP and type II diabetes, suffering from xerostomia were studied. All patients underwent questioning, dental examination, periodontal status scoring, salivary flow rate assessment and saliva pH test. Patients were randomly divided into two groups: experiment and control. Monitoring was carried out for 3 months. All patients received professional tooth cleaning, after which the experimental group was instructed to use a toothpaste containing xylitol and alginate during three months, while the control groups was instructed to keep using their own toothpaste. Patients were reexamined after 3 months.
Results. The experimental group which used the xylitol and alginate toothpaste demonstrated improvement in all parameters: periodontal status, salivary flow rate and saliva pH in comparison with the control group. No irritating effect on the sensitive mucous membrane was recorded.
Conclusion. The presence of xylitol, alginate and a natural plant component (chamomile extract) in the toothpaste seem to provide notable anti-inflammatory and moisturizing effects. The tested toothpaste contains no antiseptics, fragrances or detergents. The absence of irritating effect on the sensitive mucous membrane allows its use without limiting the duration of use.

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