Microbiological substantiation of application of phytopreparations in treatment of inflammatory periodontal diseases
https://doi.org/10.33925/1683-3759-2019-24-3-196-202
Abstract
Relevance: Inflammatory-destructive periodontal diseases are the most complicated and became the main cause of tooth loss in adult population. Herbal medicines have a variety of pharmacological properties, so the development and introduction of new forms for the treatment of inflammatory periodontal diseases is an urgent task today.
Purpose – experimental evaluation of effectiveness of the use of herbal medicines “Tonzinal” and “CM-1” in relation to the priority periodontal pathogenes.
Materials and methods: in experimental studies, the basis for the experiment was the system for the cultivation of microorganisms in real time – the Revers-Spinner RTS-1 bioreactor. With the priority strains of periodontitis pathogens, the study of the growth dynamics of the culture was carried out in several parallels.
Results: herbal medicines “CM-1” and “Tonsinal” has a multilateral therapeutic effect, exerting a diverse influence on the key stages of development of such bacterial populations as Aggregatibacter actinomycetemcomitans, Streptococcus constellatus, Candida albicans.
Conclusion: tan integrated approach in the treatment of patients with inflammatory periodontal diseases is promising and will contribute to a more prolonged remission and increase the effectiveness of treatment.
About the Authors
S. A. Abdurakhmanova
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
MD of the department of periodontology
Russian Federation
MD of the department of periodontology
G. S. Runova
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
PhD, Associate Professor of the department of periodontology
Russian Federation
PhD, Associate Professor of the department of periodontology
M. S. Podporin
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Junior research fellow of NIMSI
Russian Federation
Junior research fellow of NIMSI
E. V. Tsareva
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Assistant Professor of the department of propedeutics of dental diseases
Russian Federation
Assistant Professor of the department of propedeutics of dental diseases
E. V. Ippolitov
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
DSc, Professor of the department of microbiology, virology, immunology
Russian Federation
DSc, Professor of the department of microbiology, virology, immunology
V. N. Tsarev
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
DSc, Professor, Director Of Scientific Research Medical-Dental Institute, chief of the department of microbiology, virology, immunology
Russian Federation
DSc, Professor, Director Of Scientific Research Medical-Dental Institute, chief of the department of microbiology, virology, immunology
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Review
For citations:
Abdurakhmanova SA, Runova GS, Podporin MS, Tsareva EV, Ippolitov EV, Tsarev VN. Microbiological substantiation of application of phytopreparations in treatment of inflammatory periodontal diseases. Parodontologiya. 2019;24(3):196-202. (In Russ.) https://doi.org/10.33925/1683-3759-2019-24-3-196-202
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