Assessment of antibacterial effectiveness of ultrasonic scaling in combination with calcium hydroxyappatite suspension among patients with type-1 diabetes

Relevance. Type-1 diabetes mellitus affects usual oral microbiome for active growth of periodontal pathogenic bacteria concentration in geometric progression, which leads to decrease in function of local immunity of oral cavity, inflammation of periodontal tissues and resorption of alveolar bone – the characteristics of chronic generalized periodontitis. This article provides analysis of qualitative and quantitative composition of microflora of periodontal pocket among type-1 diabetes patients before and after conservative periodontal therapy using ultrasonic treatment technique with a polishing suspension based on calcium hydroxide («Vector Paro», Durr Dental).

Purpose. To evaluate the antibacterial effectiveness of professional oral hygiene complex with the additional treatment of periodontal pockets with «Vector Paro» device among patients with type-1 diabetes and chronic generalized mild periodontitis.

Materials and methods. 30 patients with chronic generalized mild periodontitis and type-1 diabetes were examined with using analyses of periodontal pockets microflora contents. All patients underwent a standard complex of professional oral hygiene and gentle periodontal therapy with the «Vector Paro» device. Re-examination was in 4 weeks.

Results. The performed complex of conservative periodontal therapy improved periodontal status in both groups, but in control group changes were more significant.

Conclusion. Dynamic monitoring of qualitative and quantitative composition of periodontal pockets in combination with conservative periodontal therapy using the «Vector Paro» apparatus improves hygienic and periodontal status among patients with type-1 diabetes.

1. I. Zharkova, M. Kabirova, L. Gerasimova. The dental status of people with insulin-dependent diabetes mellitus. Periodontology. 2017;22(4):14-16. (In Russ.). https://elibrary.ru/item.asp?id=32619737.

2. K. Karakov, G. Kasimova, A. Eremenko, E. Markarova, N. Vanchenko. The influence of components of the metabolic syndrome on the development of chronic generalized periodontitis. Periodontology. 2017;22(1):15-19. (In Russ.). https://elibrary.ru/item.asp?id=29233666.

3. F. Z. Mirsaeva, T. V. Khanov, T. N. Kuznetsova. Sensitivity of periodontal-pathological microflora and Candida fungi to dual probiotic. Periodontology. 2019;24(4):323-327. (In Russ.). https://doi.org/10.33925/1683-3759-2019-24-4-323-327.

4. L. Yu. Orehova, A. A. Aleksandrova, R. S. Musaeva, E. V. Posohova. Osobennosti stomatologicheskogo statusa u pacientov s saharnym diabetom i beremennyh zhenshhin. Mery profilaktiki stomatologicheskih zabolevanij u dannyh grupp pacientov. Parodontologiya. 2014;4:18-25 (In Russ.). https://elibrary.ru/item.asp?id=22872753.

5. L. Yu. Orehova, I. A. Gorbacheva, L. A. Shestakova, R. S. Musaeva, E. S. Silina, T. V. Demchenko, D. M. Nejzberg. Metabolicheskie aspekty patogeneza vospalitelnyh zabolevanij parodonta u bolnyh saharnym diabetom. Parodontologiya. 2012;3:7-11. (In Russ.). https://elibrary.ru/item.asp?id=18258259.

6. P. Graziani, S. Gennal, A. Solini, M. Petrini. A systematic review and meta-analysis of epidemiologic observational evidence on the effect of periodontal disease on diabetes: An update of the review of the EFP-AAP workshop. Journal of Clinical Periodontology. 2018;45(2):167-187. https://doi.org/10.1111/jcpe.12837.

7. D. Polak, L. Shapira. An update of the evidence for pathogenic mechanisms that may link periodontitis and diabetes. Journal of Clinical Periodontology, 2018;45(2):150-166. https://doi.org/10.1111/jcpe.12803.

8. D. Domenyuk, B. Davydov, F. Gilmiyarova, L. Ivchenko. The influence of severity of diabetes mellitus type i in children on the dental status and the immunological, biochemical indicators of blood serum and oral fluid. Part II. Periodontology. 2017;22(3):36-41. (In Russ.). https://elibrary.ru/item.asp?id=30060555.

9. N. V. Prozorova, K. E. Mamykin. Ocenka vliyaniya gigieny` polosti rta na sostoyanie tkanej parodonta u bolnyh saharnym diabetom. Vestnik Novgorodskogo gosudarstvennogo universiteta. 2015;2:86-88. (In Russ.). https://elibrary.ru/item.asp?id=23652155.

10. E. S. Korneeva, N. P. Filkova, A. M. Mkrtumyan, V. G. Atrushkevich. Parodontalnyj sindrom pri saharnom diabete: chto pervichno Lechenie i profilaktika. 2013;2:164-165. (In Russ.). https://elibrary.ru/item.asp?id=20296233.

11. L. Y. Orekhova, E. S. Loboda, E. V. Grinenko, R. S. Musaeva.. The effectiveness of complex conservative periodontal therapy using a gentle treatment technique by ultrasonic apparatus with calcium hydroxide polishing suspension among patients with type 1 diabetes and chronic generalized periodontitis.Periodontology. 2019;24(3):223-231. (In Russ.). https://doi.org/10.33925/16833759-2019-24-3-223-231.

12. G. V. Kukushkin, E. G. Starostina. Infections in diabetics (lecture) RMJ. 2016;20:1327-1333. (In Russ.). https://www.elibrary.ru/item.asp?id=28124431.

13. K.I. Agenova, R. K. Kunanbayev, M. S. Abaydilnina , Zh. S. Rzayeva. Materials of the Central Federal University scientific and practical conference Federal district of the Russian Federation with international participation «Dental and somatic diseases in children: etiopathogenetic aspects of their relationships, features of prevention, diagnostics and treatment». Tver`. 2013:14-16. (In Russ.). https://elibrary.ru/item.asp?id=21265640.

14. P. Stanko, L. Izakovicova Holla. Bidirectional association between diabetes mellitus and inflammatory periodontal disease. A review. Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia. 2014;158:35-38. DOI: 10.5507/bp.

15. M. Kumar, L. Mishra, R. Mohanty, R. Nayak. "Diabetes and gum disease: the diabolic duo". Diabetes & metabolic syndrome. 2014;8: 255-258 DOI: 10.1016/j.dsx.2014.09.022.

16. L. F. Wolff. Diabetes and periodontal disease. American journal of dentistry. 2014;27:127-128. https://doi.org/10.1590/1678-7757201302106.

17. T. F. Wang, I. A. Jen, C. Chou, Y. P. Lei. Effects of periodontal therapy on metabolic control in patients with type 2 diabetes mellitus and periodontal disease: a meta-analysis. Medicine (Baltimore). 2014;93:e292. https://doi.org/10.1097/MD.0000000000000292.

18. M. Kumar, L. Mishra, R. Mohanty, R. Nayak. Diabetes and gum disease: the diabolic duo. Diabetes & metabolic syndrome. 2014;8:255-258. https://doi.org/10.1016/j.dsx.2014.09.022.