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Dynamics of glutathione system indices in patients with nonremovable orthopedic prostheses

Abstract

The level of thiol SH-groups and the activity of glutathione reductase in the oral fluid of patients with non-removable ceramic and cermet structures have been determined.

57 patients with cermet and ceramic non-removable bridges were examined. The average age of the patients was 36.3 ± 3.55 years. The study included patients who did not have more than 3 teeth. A total of 137 non-removable bridges were found, of which 61 were ceramic-metal and 76 ceramics were whole-ceramic. The patients were divided into two groups: group I — 25 patients with cermet removable bridge restorations; Group II — 32 patients with whole-ceramic restorations.

After 6 months. after prosthetics in comparison with the initial, the concentration of thiol groups in patients with cermet prosthesis increased by 21.1%, in patients with ceramic prostheses — by 27.2% (p <0.05). After 6 months. the activity of the enzyme in patients of the I group was higher than the initial activity by 27.4% (p <0.05) and above the activity, which was observed after 7 days, by 21.6%. At this stage of the study, the GR activity was below the control one by 7.8%. In patients of group II after 6 months. after prosthetics, the enzyme activity was higher than the baseline by 45.6% (p <0.05) and 26.4% (p <0.05) higher than 7 days later. In patients with ceramic restorations, GR activity after 6 months. practically did not differ from the control one.

About the Authors

N. A. Panakhov
Азербайджанский медицинский университет
Azerbaijan


A. E. Kerimova
Азербайджанский медицинский университет
Azerbaijan


References

1. Galonskiy V. G., Radkevich A. A., Pulikov A. S. i dr. Klinicheskie priznaki, morfologiya tkaney proteznogo lozha, metody reabilitatsii bol’nykh s ektodermal’noy displaziey i vrozhdennoy adentiey // Stomatologiya detskogo vozrasta i pro-filaktika. 2011. T 10. № 4. S. 29-40.

2. Zhulev E. N. Metallokeramicheskie protezy.— N. Novgorod: Izd-vo NGMA, 2005.— 288 s.

3. Ivanova A. V., Zheleznyy P A., Antonov A. R., Safronov I. D. Pro- i antioksidantnyy potentsial rotovoy zhidkosti pri zubochelyustnom protezirovanii // Fundamental’nye issledovaniya. 2009. № 2. S. 90-91.

4. Kudryavtseva T V., Cheminava N. R. Vliyanie mineral’nogo sostava rotovoy zhidkosti na stomatologicheskoe i somaticheskoe zdorov’e // Parodontologi-ya. 2016. T 21. № 4 (81). S. 17-23.

5. Meditsinskaya laboratornaya diagnostika: programmy i algoritmy / pod red. A. I. Karpishchenko. 3-e izd.— M.: GEOTAR-Media, 2014.— 696 s.

6. Petrikas O. A., Petrikas I. V., Voroshilin Yu.G., Korol’kov A. B. Otsenka funktsional’nykh vozmozhnostey periodonta opornykh zubov adgezivnykh mostovidnykh protezov s pomoshch’yu periotestirovaniya // Parodontologiya. 2010. № 3. S. 50-53.

7. Sorokin E. V. Osobennosti protezirovaniya pri chastichnoy potere zubov v sovremennoy ortopedicheskoy stomatologii // Nauchnoe obozrenie. Meditsinskie nauki (Saratov). 2017. № 4. S. 106-109.

8. Trifonov B. V., Kopytov A. A., Agapov N. N., Anisimova O. O. Ispol’zovanie chisel Khaunsfilda kak kharakteristiki restavratsionnykh materialov // Endodontiya today. 2011. № 1. S. 43-48.

9. Khalimskaya K. M. Aspekty tsel’nokeramicheskogo protezirovaniya // Nauchnoe obozrenie. Meditsinskie nauki (Saratov). 2017. № 3. S. 83-86.

10. Tsimbalistov A. V., Kopytov A. A. Izmenenie gidrodinamiki parodonta opornykh zubov v protsesse adaptatsii k mostovidnym protezam // Parodontologiya. 2015. T 2. № 75. S. 10-13.

11. Baudouin-Cornu P, Lagniel G., Kumar C. et al. Glutathione degradation is a key determinant of glutathione homeostasis // J. Biol. Chem. 2012. Vol.287. P. 4552-4561.

12. Chen Yi-Ju, Lu Cheng-Tsung, Lee Tzong-Yi, Chen Yu-Ju. dbGSH: a database of S-glutathionylation // Bioinformatics, 2014. Vol.30. Issue 16. P 2386-2388.

13. Ho G. W., Matinlinna J. P Insights on ceramics as dental materials. Part I: ceramic material types in dentistry // Springer. 2011. Vol. 3. Issue 3. P. 109-115.

14. Van Nort R., Barbour M. E. Introduction to dental Materials. 4-th ed.— Edinburgh; NewYork: Mosby Elsevier, 2013.— 246 p.

15. Wayner D. Radical-trapping antioxidants in vitro and in vivo // Bioelectrochem Bioenerg. 1987. № 1-3. Р 219-229.


Review

For citations:


Panakhov NA, Kerimova AE. Dynamics of glutathione system indices in patients with nonremovable orthopedic prostheses. Parodontologiya. 2018;24(4):119-122. (In Russ.)

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ISSN 1683-3759 (Print)
ISSN 1726-7269 (Online)