Herpesvirus infection as one of the causes of anemia

Abstract

To prove the influence of herpesvirus infection on the occurrence of anemia of chronic disease. The study involved 75 people suffering from herpes-viral infection. 3 groups were allocated: the first group (25 people) received acyclovir 1 tablet (200 mg) 5 times a day, 5 days; The 2nd group (25 people) used famvir for 1 tablet (250 mg) 2 times a day, 5 days; The third group (25 people) — famvir 1 tablet (250 mg) 2 times a day, 5 days and kagocel 2 tablets (12 mg) 3 times a day, 5 days. All subjects examined at the time of treatment showed an increase in the content of IL-1β mRNK and TNF-α and a decrease in mRNK of IL-8 and IL-10; on day 14 of the study, a decrease in IL-1β mRNK and TNF-α mRNK and an increase in IL-10 mRNK. In the study of erythrocyte indices — the average volume of erythrocytes and the average hemoglobin content in erythrocyte and the parameters of iron-serum iron metabolism and the total iron binding capacity of the serum, slight deviations from the norm were obtained. Thus, we concluded that the cause of anemia, in addition to the lack of iron, can be chronic herpesvirus infection, and thus timely treatment of a viral infection excludes the use of ferrotherapy.