Model of development, prevention and treatment of oral lichen planus. Part II
https://doi.org/10.25636/PMP.1.2019.1.10
Abstract
Relevance. Currently, system-wide patterns of development, progression of oral lichen planus have not been studied enough. The questions of substantiation of expedient therapeutic and prophylactic measures for this disease with characteristic risk factors have not been worked out in many respects.
Purpose. Identifcation of new system-wide regularities of oral lichen planus based on the development of a model for its development, prevention and treatment.
Materials and methods. The study design included: the development of a model for the development, progression, prevention and treatment of oral lichen planus; clinical dental examination of 350 patients with oral lichen planus (the diagnosis was made on the basis of clinical data and the results of fluorescent diagnostics); evaluation of the effectiveness of a set of measures, including the prescription of drugs (Imudon, Kudesan, Tenoten).
Results. New system-wide regularities of lichen planus are revealed. For the frst time, the relative frequencies and intensities of transitions of various forms of lichen planus from one to another are estimated. A method is proposed for estimating the moment of saturation of the therapeutic and prophylactic effect of a complex of measures on the oral mucosa with lichen planus using fluorescent diagnostics. The temporal characteristics of this moment were determined during the performance of the therapeutic and prophylactic complex.
Summary. The developed model will allow, without signifcant time and material costs, justify therapeutic and prophylactic measures that are expedient for various groups of the population in case of oral lichen planus of the oral mucosa.
About the Authors
L. Yu. Orekhova
Federal State Educational Institution of Higher Education «First St. Petersburg State Medical University named аcademician I.P. Pavlov» of the Ministry of Health of the Russian Federation
Russian Federation
DMS, Professor, Head of Department
Department of Dentistry Therapeutic and Periodontology
Russian Federation
DMS, Professor, Head of Department
Department of Dentistry Therapeutic and Periodontology
M. V. Osipova
Federal State Educational Institution of Higher Education «First St. Petersburg State Medical University named аcademician I.P. Pavlov» of the Ministry of Health of the Russian Federation
Russian Federation
DMS, Associate Professor
Department of Dentistry Therapeutic and Periodontology
Russian Federation
DMS, Associate Professor
Department of Dentistry Therapeutic and Periodontology
А. А. Ladyko
Federal State Educational Institution of Higher Education «First St. Petersburg State Medical University named аcademician I.P. Pavlov» of the Ministry of Health of the Russian Federation
Russian Federation
Doctor Dermatovenerologist
Department of Dentistry Therapeutic and Periodontology
Russian Federation
Doctor Dermatovenerologist
Department of Dentistry Therapeutic and Periodontology
References
1. Buzov D. A., Haritonova M. P., Dorofeev A. V. Diagnostika raka slizistoj obolochki polosti rta v krupnom industrial'nom centre // Ural'skij medicinskij zhurnal. 2012. №4. S. 35-36.
2. Vil'danov M. N. Osobennosti stomatologicheskogo statusa u pacientov s keratozami slizistoj obolochki polosti rta // Medicinskij vestnik Bashkortastana. 2014. №6 (9). S. 47-50.
3. Danilevskij N. F., Leont'ev V. K., Nesin A. F., Rahnij Zh. I. Zabolevaniya slizistoj obolochki polosti rta / Izmeneniya slizistoj obolochki polosti rta pri dermatozah s autoimunnym komponentom. – M., 2001. – 271 s.
4. Leont'eva E. S., Kuznecova R. G., Muhamedzhanova L. R. Krasnyj ploskij lishaj i generalizovannyj parodontit: circulus vitiosus ili sochetannaya patologiya? // Prakticheskaya medicina. 2012. T. 2. №8 (64). S. 131-135.
5. Makedonova Yu. A., Porojskaya A. V., Firsova I. V., Porojskij S. V. Optimizaciya mestnoj terapii bol'nyh krasnym ploskim lishaei slizistoj obolochki polosti rta // Parodontologiya. 2017. №4. S. 30-34.
6. Olisova O. Ju., Chikin V. V., Mineeva A. A. Federal'nye klinicheskie rekomendacii po vedeniju bol'nyh krasnym ploskim lishaem. – M., 2015. – 19 s.
7. Orekhova L.Yu. Prognozirovanie ehffektivnosti slozhnyh ltchebno-profilakticheskih program pri vospalitel’nyh zabolevaniah parodonta // Parodontologiya. 2009. №3 (52). С. 51-55.
8. Rol’ vracha-parodontologa v diagnostike obshchesomaticheskoj patologii //Parodontologiya. 2010. №4 (57). С. 20-25.
9. Osipova M. V. Prognozirovanie ehffektivnosti lechebno-profilakticheskih meropriyatij pri stomatologicheskih zabolevaniyah // Uchenye zapiski SPbGMU im. akad. I.P. Pavlova. 2013. №2. S. 118-122.
10. Osipova M. V. Stomatologicheskie modeli obshchesomaticheskoj patologii // Stomatolog. 2012. №1 (4). S. 29-35.
11. Osipova M. V. Obshchesistemnye zakonomernosti razvitiya kariesa i ego oslozhnenij u naseleniya megapolisa // Institut stomatologii. 2012. T. 2. №55. S.20-21.
Review
For citations:
Orekhova LY, Osipova MV, Ladyko АА. Model of development, prevention and treatment of oral lichen planus. Part II. Parodontologiya. 2019;24(1):57-62. (In Russ.) https://doi.org/10.25636/PMP.1.2019.1.10
Views:
907
Email this article 