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Arresting the pain syndrome after biopsy collection in oral mucosal diseases

https://doi.org/10.33925/1683-3759-2022-27-3-250-257

Abstract

Relevance. Diagnosis of oral mucosa diseases is very difficult. Heterogeneity of the oral mucosa disease manifestation often requires invasive diagnostic methods, which cause the pain syndrome. Timely and complete pain syndrome relief and the impact on all phases of the w ound healing process allow faster patient rehabilitation. The study aimed to examine the effect of Ketanov MD and Cifran CT on the wound process and the pain syndrome intensity after incisional and excisional biopsies to verify the oral mucosa pathology.

Materials and methods. The study surveyed 30 people with oral mucosal diseases. The patients (30 subjects) formed two groups: excisional (10 people) and incisional biopsy (20 people). In these groups, we clinically evaluated the course of the wound process, the pain syndrome intensity, oedema phenomena, hyperemia, and the exudate presence. We analysed the quality of life of such patients using a validated Russian v ersion of the questionnaire.

Results. On the 3rd day after the biopsy, on top of the generally accepted treatment of oral mucosal diseases and Ketorol MD and Cifran CT intake, the patients noted moderate aching and discomfort when talking and eating. After 14 days, all patients showed an improvement in qualitative and quantitative parameters, the absence of pain and the development of reinfection on therapy with non-steroidal anti-inflammatory and antibacterial drugs.

Conclusion. These drugs have a positive effect on the course of the phases of the wound process. They help reduce the pain response and contribute to faster patient rehabilitation af ter the biopsies in oral mucosal diseases.  

About the Authors

Yu. A. Makedonova
Volgograd State Medical University; Volgograd Medical Scientific Center
Russian Federation

Yuliya A. Makedonova, DDS, PhD, DSc, Associate Professor, Head of the Department of Dentistry, Institute of Continuous Medical and Pharmaceutical Education; Senior Researcher

Volgograd



L. V. Zhuravlev
Pskov Regional Clinical Hospital
Russian Federation

Lev V. Zhuravlev, DDS, maxillofacial surgeon, Pskov Regional Clinical Hospital

Pskov



M. V. Kabytova
Volgograd State Medical University
Russian Federation

Maria V. Kabytova, DDS, PhD, Associate Professor, Department of Dentistry, Institute of Continuous Medical and Pharmaceutical Education

Volgograd



S. V. Dyachenko
Volgograd State Medical University
Russian Federation

Svetlana V. Dyachenko, DMD, Assistant Professor, Department of Dentistry, Institute of Continuing Medical and Pharmaceutical Education

Volgograd



О. Yu. Afanaseva
Volgograd State Medical University
Russian Federation

Olga Yu. Afanasyeva, DDS, PhD, Associate Professor, Department of Dentistry, Institute of Continuing Medical and Pharmaceutical Education

Volgograd



S. M. Gacenko
Volgograd State Medical University
Russian Federation

Sergey M. Gatsenko, DDS, PhD, Associate Professor, Department of Prosthodontics

Volgograd



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Review

For citations:


Makedonova YA, Zhuravlev LV, Kabytova MV, Dyachenko SV, Afanaseva ОY, Gacenko SM. Arresting the pain syndrome after biopsy collection in oral mucosal diseases. Parodontologiya. 2022;27(3):250-257. (In Russ.) https://doi.org/10.33925/1683-3759-2022-27-3-250-257

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ISSN 1683-3759 (Print)
ISSN 1726-7269 (Online)