Influence long-term use of statins on the course of inflammatory periodontal diseases in coronary artery disease patients

Abstract

The relevance of the study is due to the high prevalence of inflammatory periodontal diseases in patients with cardiovascular pathology. Currently, for the treatment of ischemic heart disease (IHD), statins are used, which, in addition to hypolipidemic action, have anti-inflammatory properties, which can lead to an increase in the pressure of the inflammatory process, not only in heart vessels, but also in paradonte.

The aim of the study was to study the effect of prolonged use of statins on the course of inflammatory periodontal diseases in patients with IHD.

Materials and methods. A dental examination and study of the quality of life of 122 patients with ischemic heart disease (IHD) were performed. Surveyed were divided into two groups depending on the duration of receiving lipid-corrective therapy.

The results of the study. It has been established that in patients with coronary artery disease who take statins for a long time, the periodontal inflammation activity and the severity of its clinical manifestations are lower than in patients not using lipid-correcting therapy, which was accompanied by improvement in certain parameters of quality of life.